Pharmacological and therapeutic effects of A3 adenosine receptor agonists
about
Potential for developing purinergic drugs for gastrointestinal diseasesPeripheral Adenosine A3 Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine H1 Receptors.N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant responseStructural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congenersAdenosine receptors as drug targets--what are the challenges?Distinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis.Role and Function of A2A and A₃ Adenosine Receptors in Patients with Ankylosing Spondylitis, Psoriatic Arthritis and Rheumatoid Arthritis.Adenosine signaling during acute and chronic disease statesExtended N(6) substitution of rigid C2-arylethynyl nucleosides for exploring the role of extracellular loops in ligand recognition at the A3 adenosine receptor.Structure-based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates.In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists.Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy.Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic painJohn Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y ReceptorsEmerging adenosine receptor agonists: an updateAdenosine A2b receptor promotes progression of human oral cancerRigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo EfficacyApoptosis and inhibition of proliferation of cancer cells induced by cordycepinMedicinal chemistry of adenosine, P2Y and P2X receptors.A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.Efficient, large-scale synthesis and preclinical studies of MRS5698, a highly selective A3 adenosine receptor agonist that protects against chronic neuropathic pain.G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactionsStructure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions.Current status and future prospects for biologic treatments of psoriasis.Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists.Truncated Nucleosides as A(3) Adenosine Receptor Ligands: Combined 2-Arylethynyl and Bicyclohexane SubstitutionsUpdate on psoriasis immunopathogenesis and targeted immunotherapy.A Key Opinion Leader interview: insight into the research and career of Dr KA Jacobson.Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor.Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?Structure-Activity Analysis of Biased Agonism at the Human Adenosine A3 Receptor.Identification of A3 adenosine receptor agonists as novel non-narcotic analgesics.New paradigms in GPCR drug discovery.Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain.Cancer and orofacial pain.Systemic Wound Healing Associated with local sub-Cutaneous Mechanical Stimulation.Allosteric interactions at adenosine A(1) and A(3) receptors: new insights into the role of small molecules and receptor dimerization.Purinergic receptors in ocular inflammation.Adenosine A3 Receptor: A promising therapeutic target in cardiovascular disease.
P2860
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P2860
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@ast
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@en
type
label
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@ast
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@en
prefLabel
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@ast
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@en
P2093
P2860
P1433
P1476
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
@en
P2093
Bruce T Liang
Kenneth A Jacobson
Sara Bar-Yehuda
P2860
P304
P356
10.1016/J.DRUDIS.2011.10.007
P577
2011-10-19T00:00:00Z