Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia. - Test2 - elhamkhani - TriplyDB

Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.

Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.

http://www.wikidata.org/entity/Q36295665

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The sense of smell, its signalling pathways, and the dichotomy of cilia and microvilli in olfactory sensory cells Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways Regulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9)Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage Epithelial Anion Transport as Modulator of Chemokine Signaling Mucociliary dysfunction in HIV and smoked substance abuse Epithelial Na(+) channel regulation by cytoplasmic and extracellular factors Microscale imaging of cilia-driven fluid flow Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways Activation of the epithelial sodium channel (ENaC) by the alkaline protease from Pseudomonas aeruginosa CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium Non-invasive airway health assessment: synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo.Model demonstrates functional purpose of the nasal cycle.Smoking is associated with shortened airway cilia ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.Effects of secretagogues on net and unidirectional liquid fluxes across porcine bronchial airways.Sodium tanshinone IIA sulfonate stimulated Cl- secretion in mouse trachea.New horizons in the treatment of cystic fibrosis.Purinergic receptors in airway epithelia.The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.Biomarkers of Exposure to New and Emerging Tobacco and Nicotine Delivery Products.Experimental human pneumococcal carriage augments IL-17A-dependent T-cell defence of the lung.Nasal potential difference to detect Na+ channel dysfunction in acute lung injury.CFTR and lung homeostasis.Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis.Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition Functional apical large conductance, Ca2+-activated, and voltage-dependent K+ channels are required for maintenance of airway surface liquid volume.Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchi.Modulation of the epithelial sodium channel (ENaC) by bacterial metalloproteases and protease inhibitors.Measurement of the airway surface liquid volume with simple light refraction microscopy.Infection by Toxoplasma gondii, a severe parasite in neonates and AIDS patients, causes impaired anion secretion in airway epithelia.Characteristics of chloride transport in nasal mucosa from patients with primary ciliary dyskinesia.Cigarette smoke exposure reveals a novel role for the MEK/ERK1/2 MAPK pathway in regulation of CFTR

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P2860

Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.

http://www.wikidata.org/entity/Q36295665

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Soluble mediators, not cilia, ...... superficial airway epithelia.

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Laura Trout

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Richard C Boucher

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Robert Tarran

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Scott H Donaldson

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P2860

Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity

State of the art: why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection?

Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.

Regulation of the epithelial sodium channel by serine proteases in human airways.

Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells

Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections

Nucleotide release provides a mechanism for airway surface liquid homeostasis

Pathophysiology and treatment of airway mucociliary clearance. A moving tale.

Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line.

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5

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127

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16636206

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cystic fibrosis

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2151517

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