3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.
about
Telomerase as a Cancer Target. Development of New MoleculesIn vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIsLeukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.Premature aging and immune senescence in HIV-infected children.Telomerase structure paves the way for new cancer therapies.Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532The combined use of known antiviral reverse transcriptase inhibitors AZT and DDI induce anticancer effects at low concentrations.Thymidine kinases share a conserved function for nucleotide salvage and play an essential role in Arabidopsis thaliana growth and development.Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
P2860
Q28079188-51E5B4D3-D8F0-437A-AF95-E0FE0D6ED6EFQ28391094-330ADAC7-6940-49AB-9A73-39FA0FC2C065Q34344690-D0763F26-2DD5-4F52-8C78-61C04C718C02Q36903898-1F4E8BF0-44BB-44C3-9614-27FF0462F3DBQ37414350-7EA115E7-83A4-4576-A95B-F47D7E21D41AQ38835615-F633B262-2078-4BAD-BBE0-8644983C46FDQ39392359-F0976604-5801-4A29-AC33-9885ECD5BE40Q40771681-CFF4F22B-948F-4F3B-AE93-1288B2A3BE69Q45353122-24F8A62A-C160-4B77-9D72-B0C897F3DDF8
P2860
3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@ast
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@en
type
label
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@ast
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@en
prefLabel
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@ast
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@en
P2093
P2860
P356
P1476
3'-Azido-2',3'-dideoxynucleosi ...... hortening in human HL60 cells.
@en
P2093
Hazuki Takahashi
Mineo Saneyoshi
Toyofumi Yamaguchi
Tsukasa Ogawara
Xiaohong Liu
Yoko Harada
Yoshiyuku Mizushina
Yuta Ogimura
P2860
P304
P356
10.1093/NAR/GKM859
P407
P577
2007-10-16T00:00:00Z