SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential. - Test2 - elhamkhani - TriplyDB

SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential.

SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential.

http://www.wikidata.org/entity/Q36403649

about

Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance An overview of IL-7 biology and its use in immunotherapy.Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection Complete diabetes protection despite delayed thymic tolerance in NOD8.3 TCR transgenic mice due to antigen-induced extrathymic deletion of T cells.Negative Regulation of Memory Phenotype CD8 T Cell Conversion by Adhesion and Degranulation-Promoting Adapter Protein.Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2 The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells.SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation.Homeostasis of memory T cells.IL-15 temporally reorients IL-10 biased B-1a cells toward IL-12 expression.SOCS regulation of the JAK/STAT signalling pathway.T cell homeostasis.Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance.MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer Suppression of cytokine signaling: the SOCS perspective.Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function.Homeostatic maintenance of T cells and natural killer cells.Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy.Diet-induced obesity in mice reduces the maintenance of influenza-specific CD8+ memory T cells.SOCS1 negatively regulates the production of Foxp3+ CD4+ T cells in the thymus.SOCS1: Regulator of T Cells in Autoimmunity and Cancer.The molecular basis of JAK/STAT inhibition by SOCS1.

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SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential.

http://www.wikidata.org/entity/Q36403649

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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SOCS-1 regulates IL-15-driven ...... ng their autoimmune potential.

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SOCS-1 regulates IL-15-driven ...... ng their autoimmune potential.

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SOCS-1 regulates IL-15-driven ...... ng their autoimmune potential.

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SOCS-1 regulates IL-15-driven ...... ng their autoimmune potential.

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SOCS-1 regulates IL-15-driven ...... ng their autoimmune potential.

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SOCS-1 regulates IL-15-driven ...... ng their autoimmune potential.

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Ann L Cornish

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Charles D Surh

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Francis R Carbone

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J Theodore Burghardt

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Robyn Starr

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Warren S Alexander

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P2860

Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells

A family of cytokine-inducible inhibitors of signalling

A new protein containing an SH2 domain that inhibits JAK kinases

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo

Structure and function of a new STAT-induced STAT inhibitor

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

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1099-1108

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10.1084/JEM.20050003

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8

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202

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William R Heath

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7548949

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2213211

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