Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity. - Test2 - elhamkhani - TriplyDB

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.

http://www.wikidata.org/entity/Q36465556

about

Cyclotide structure-activity relationships: qualitative and quantitative approaches linking cytotoxic and anthelmintic activity to the clustering of physicochemical forces Antimicrobial peptides in 2014 In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: A proof-of-concept study using the integrin-binding RGD motif Computational Design of Hypothetical New Peptides Based on a Cyclotide Scaffold as HIV gp120 Inhibitor Gene coevolution and regulation lock cyclic plant defence peptides to their targets Peptide and protein-based inhibitors of HIV-1 co-receptors Cycloviolacin O2 (CyO2) suppresses productive infection and augments the antiviral efficacy of nelfinavir in HIV-1 infected monocytic cells.Asteropsins B-D, sponge-derived knottins with potential utility as a novel scaffold for oral peptide drugs Peptides and peptidomimetics as immunomodulators.Dynamic scenario of membrane binding process of kalata b1 Bivalent ligands targeting chemokine receptor dimerization: molecular design and functional studies.The evolution of Momordica cyclic peptides.Rapid parallel synthesis of bioactive folded cyclotides by using a tea-bag approach.Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum.Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).Recombinant Expression and Phenotypic Screening of a Bioactive Cyclotide Against α-Synuclein-Induced Cytotoxicity in Baker's Yeast.Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae.Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration.Design of a MCoTI-Based Cyclotide with Angiotensin (1-7)-Like Activity.Chemical and biological production of cyclotides.Database-Guided Discovery of Potent Peptides to Combat HIV-1 or Superbugs Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis.Joseph Rudinger memorial lecture: discovery and applications of cyclotides.Cyclotides as grafting frameworks for protein engineering and drug design applications.Structure-based and fragment-based GPCR drug discovery.Cystine-knot peptides: emerging tools for cancer imaging and therapy.Cyclotides: a natural combinatorial peptide library or a bioactive sequence player?Review cyclic peptides on a merry-go-round; towards drug design.Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization.Discovery and optimization of peptide macrocycles.Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and Therapeutic Perspectives in the Postantibiotic Era.Cyclotides: Overview and Biotechnological Applications.Making ends meet: chemically mediated circularization of recombinant proteins.In vivo Evaluation of an Engineered Cyclotide as Specific CXCR4 Imaging Reagent.Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases.Easy and rapid binding assay for functional analysis of disulfide-containing peptides by a pull-down method using a puromycin-linker and a cell-free translation system.

P2860

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P2860

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.

http://www.wikidata.org/entity/Q36465556

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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type

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Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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prefLabel

Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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Design of a novel cyclotide-ba ...... ciency virus (HIV)-1 activity.

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P2093

Alexander Shekhtman

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Helen Ha

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Julio A Camarero

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Nouri Neamati

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Subhabrata Majumder

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Teshome L Aboye

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P2860

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

Involvement of chemokine receptors in breast cancer metastasis

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif

Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis

Small-molecule antagonists of CCR5 and CXCR4: a promising new class of anti-HIV-1 drugs

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

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