Hypusine modification for growth is the major function of spermidine in Saccharomyces cerevisiae polyamine auxotrophs grown in limiting spermidine.
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Post-translational modification by β-lysylation is required for activity of Escherichia coli elongation factor P (EF-P)Metabolic reprogramming and metabolic dependency in T cellsTransfer RNA travels from the cytoplasm to organellesBinding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteineDimerization of the yeast eukaryotic translation initiation factor 5A requires hypusine and is RNA dependent.Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae.Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injuryeIF5A promotes translation elongation, polysome disassembly and stress granule assemblyBiochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulationFunctional significance of eIF5A and its hypusine modification in eukaryotesThe role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongationInhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A.Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells.Upregulation of a novel eukaryotic translation initiation factor 5A (eIF5A) in dengue 2 virus-infected mosquito cells.The hypusine-containing translation factor eIF5A.Evolution and multiplicity of arginine decarboxylases in polyamine biosynthesis and essential role in Bacillus subtilis biofilm formation.Inactivation of eukaryotic initiation factor 5A (eIF5A) by specific acetylation of its hypusine residue by spermidine/spermine acetyltransferase 1 (SSAT1).Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.Bulk segregant analysis followed by high-throughput sequencing reveals the Neurospora cell cycle gene, ndc-1, to be allelic with the gene for ornithine decarboxylase, spe-1Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.Effects of novel C-methylated spermidine analogs on cell growth via hypusination of eukaryotic translation initiation factor 5A.Loss of elongation factor P disrupts bacterial outer membrane integrityMicroarray studies on the genes responsive to the addition of spermidine or spermine to a Saccharomyces cerevisiae spermidine synthase mutant.Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development.Current status of the polyamine research fieldMouse models to investigate the function of sperminePolyamines are not required for aerobic growth of Escherichia coli: preparation of a strain with deletions in all of the genes for polyamine biosynthesis.Mammalian polyamine metabolism and functionPlant polyamine catabolism: The state of the art.Strategies to ameliorate abiotic stress-induced plant senescence.Selective regulation of polyamine metabolism with methylated polyamine analogues.Polyamines are oncometabolites that regulate the LIN28/let-7 pathway in colorectal cancer cells.A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.Yeast response and tolerance to benzoic acid involves the Gcn4- and Stp1-regulated multidrug/multixenobiotic resistance transporter Tpo1.Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload.The roles of polyamines in microorganisms.Molecular events leading to death of Leishmania donovani under spermidine starvation after hypericin treatment.Scots pine aminopropyltransferases shed new light on evolution of the polyamine biosynthesis pathway in seed plants.Polyamines regulate cell growth and cellular methylglyoxal in high-glucose medium independently of intracellular glutathione.Signals of aging associated with lower growth rates in Kluyveromyces lactis cultures under nitrogen limitation.
P2860
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P2860
Hypusine modification for growth is the major function of spermidine in Saccharomyces cerevisiae polyamine auxotrophs grown in limiting spermidine.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Hypusine modification for grow ...... grown in limiting spermidine.
@ast
Hypusine modification for grow ...... grown in limiting spermidine.
@en
type
label
Hypusine modification for grow ...... grown in limiting spermidine.
@ast
Hypusine modification for grow ...... grown in limiting spermidine.
@en
prefLabel
Hypusine modification for grow ...... grown in limiting spermidine.
@ast
Hypusine modification for grow ...... grown in limiting spermidine.
@en
P2093
P2860
P356
P1476
Hypusine modification for grow ...... grown in limiting spermidine.
@en
P2093
Herbert Tabor
Manas K Chattopadhyay
Myung Hee Park
P2860
P304
P356
10.1073/PNAS.0710970105
P407
P577
2008-05-01T00:00:00Z