Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
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5'-UTR RNA G-quadruplexes: translation regulation and targetingCrystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformationIdentification and characterization of putative methylation targets in the MAOA locus using bioinformatic approachesQGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs.Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expressionIdentification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening.Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines.A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional rolesSuppression of gene expression by G-quadruplexes in open reading frames depends on G-quadruplex stability.Identification and characterization of RNA guanine-quadruplex binding proteins.The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzymeDiscovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression.Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation.Translational repression of cyclin D3 by a stable G-quadruplex in its 5' UTR: implications for cell cycle regulationDiscovery of widespread GTP-binding motifs in genomic DNA and RNARole of conserved cis-regulatory elements in the post-transcriptional regulation of the human MECP2 gene involved in autism.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?Altered biochemical specificity of G-quadruplexes with mutated tetrads.The tale of RNA G-quadruplex.RNA G-quadruplexes: emerging mechanisms in diseaseMechanical insights into ribosomal progression overcoming RNA G-quadruplex from periodical translation suppression in cells.Stability of RNA quadruplex in open reading frame determines proteolysis of human estrogen receptor α.RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5'-UTR of KRAS oncogene represses translation.Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.Loop flexibility in human telomeric quadruplex small-molecule complexes.Transfecting RNA quadruplexes results in few transcriptome perturbationsIrregular G-quadruplexes Found in the Untranslated Regions of Human mRNAs Influence Translation.Stimulation of ribosomal frameshifting by RNA G-quadruplex structures.The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression.A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology.QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences.5'-UTR G-quadruplex structures acting as translational repressors.Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex.Calculation of hydrodynamic properties for G-quadruplex nucleic acid structures from in silico bead models.G-quadruplexes as tools for synthetic biology.Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes.Functional 5' UTR mRNA structures in eukaryotic translation regulation and how to find them.
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P2860
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@en
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@nl
type
label
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@en
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@nl
prefLabel
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@en
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@nl
P2093
P2860
P356
P1476
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes.
@en
P2093
Jörg S Hartig
Kangkan Halder
Markus Wieland
P2860
P304
P356
10.1093/NAR/GKP696
P407
P577
2009-09-09T00:00:00Z