SH2 domains: modulators of nonreceptor tyrosine kinase activity.
about
Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherinHeme controls the regulation of protein tyrosine kinases Jak2 and SrcAn adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl bindingThe Fyn-ADAP Axis: Cytotoxicity Versus Cytokine Production in Killer CellsNoncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase IIStructural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling DeregulationTargeting the SH2-Kinase Interface in Bcr-Abl Inhibits LeukemogenesisStructural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic HelixSuperdomains in the protein structure hierarchy: The case of PTP-C2A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determinationThe SH2 domain regulates c-Abl kinase activation by a cyclin-like mechanism and remodulation of the hinge motionTheoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation.NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors.Distal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk)Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.The regulation of N-methyl-D-aspartate receptors by Src kinase.Hierarchical graphs for rule-based modeling of biochemical systemsDimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structureHistone acetyltransferases: Rising ancient counterparts to protein kinases.Molecular physiology of the tensin brotherhood of integrin adaptor proteins.Systematic identification of phosphorylation-mediated protein interaction switches.A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency.Phosphotyrosine recognition domains: the typical, the atypical and the versatile.Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton.c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution.Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry.Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases.The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles.Evolution of the JAK-STAT pathway.Mutations in tyrosine kinase and tyrosine phosphatase and their relevance to the target therapy in hematologic malignancies.Identification and characterization of tyrosine kinases in anole lizard indicate the conserved tyrosine kinase repertoire in vertebrates.Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity.Functionally Altered SH2 Domains for Biochemical Studies: Loss-of-Function Mutant and Domain Concatenation.Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling.Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation.Purification, crystallization and preliminary X-ray diffraction analysis of the Fyn SH2 domain and its complex with a phosphotyrosine peptide.On the Control of TCR Phosphorylation.Fusion of the genes ataxin 2 like, ATXN2L, and Janus kinase 2, JAK2, in cutaneous CD4 positive T-cell lymphoma.
P2860
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P2860
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@en
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@nl
type
label
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@en
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@nl
prefLabel
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@en
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@nl
P2860
P50
P1476
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
@en
P2860
P304
P356
10.1016/J.SBI.2009.10.001
P577
2009-11-18T00:00:00Z
2009-12-01T00:00:00Z