Signatures of mutation and selection in the cancer genome.
about
Warburg effect and translocation-induced genomic instability: two yeast models for cancer cellsFOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinomaA systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cellsPassenger deletions generate therapeutic vulnerabilities in cancerEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthMelanoma genome sequencing reveals frequent PREX2 mutationsInduction of human epithelial stem/progenitor expansion by FOXM1The genomic complexity of primary human prostate cancerMutational processes molding the genomes of 21 breast cancersDistant metastasis occurs late during the genetic evolution of pancreatic cancerMutant proteins as cancer-specific biomarkersMassive genomic rearrangement acquired in a single catastrophic event during cancer developmentConvergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancerRetinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategiesCan Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical reviewNetwork biomarkers reveal dysfunctional gene regulations during disease progressionCommon fragile sites: genomic hotspots of DNA damage and carcinogenesisEvolution of the cancer genomeTumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogasterSomatic SF3B1 mutation in myelodysplasia with ring sideroblastsTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseWWOX, the chromosomal fragile site FRA16D spanning gene: its role in metabolism and contribution to cancerThe somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapesExploiting FOXM1-orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosisAnalysis of next-generation genomic data in cancer: accomplishments and challengesInitiation of genome instability and preneoplastic processes through loss of Fhit expressionChromosome fragile sites in Arabidopsis harbor matrix attachment regions that may be associated with ancestral chromosome rearrangement eventsBreakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer typesMolecular integrative clustering of Asian gastric cell lines revealed two distinct chemosensitivity clustersEvolution of the cancer genomeCancer in light of experimental evolutionThe tumour suppressor CYLD regulates the p53 DNA damage responseClonal evolution in cancerThe life history of 21 breast cancersThe genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroupsThe causes and consequences of genetic heterogeneity in cancer evolutionThe clonal and mutational evolution spectrum of primary triple-negative breast cancersVentX trans-activates p53 and p16ink4a to regulate cellular senescenceGenome-wide copy number analysis of single cells.Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.
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Signatures of mutation and selection in the cancer genome.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Signatures of mutation and selection in the cancer genome.
@en
Signatures of mutation and selection in the cancer genome.
@nl
type
label
Signatures of mutation and selection in the cancer genome.
@en
Signatures of mutation and selection in the cancer genome.
@nl
prefLabel
Signatures of mutation and selection in the cancer genome.
@en
Signatures of mutation and selection in the cancer genome.
@nl
P2093
P2860
P50
P356
P1433
P1476
Signatures of mutation and selection in the cancer genome.
@en
P2093
Adam P Butler
Beiyuan Fu
Chris D Greenman
Ciara Fahey
David Beare
Fengtang Yang
Graham R Bignell
Helen Davies
Jenny M Andrews
Jonathon Hinton
P2860
P2888
P304
P356
10.1038/NATURE08768
P407
P50
P577
2010-02-01T00:00:00Z