A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint. - Test2 - elhamkhani - TriplyDB

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint.

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint.

http://www.wikidata.org/entity/Q41544497

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Antiproliferative Fate of the Tetraploid Formed after Mitotic Slippage and Its Promotion; A Novel Target for Cancer Therapy Based on Microtubule Poisons The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment Structure of an intermediate conformer of the spindle checkpoint protein Mad2 Rab6a is a novel regulator of meiotic apparatus and maturational progression in mouse oocytes Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.How the SAC gets the axe: Integrating kinetochore microtubule attachments with spindle assembly checkpoint signaling.Important molecular genetic markers of colorectal cancer.The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma.Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells.Playing polo during mitosis: PLK1 takes the lead.The RZZ complex requires the N-terminus of KNL1 to mediate optimal Mad1 kinetochore localization in human cells.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis.Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties Widespread Recurrent Patterns of Rapid Repeat Evolution in the Kinetochore Scaffold KNL1.Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation.Basis of catalytic assembly of the mitotic checkpoint complex.A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.Bub1/BubR1: swiss army knives at kinetochores.Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores.Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.HDAC3 promotes meiotic apparatus assembly in mouse oocytes by modulating tubulin acetylation.Mechanisms of Mitotic Kinase Regulation: A Structural Perspective.The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.MAD1: Kinetochore Receptors and Catalytic Mechanisms.Kinase and Phosphatase Cross-Talk at the Kinetochore.Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment Analysis of the role of GSK3 in the mitotic checkpoint

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A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint.

http://www.wikidata.org/entity/Q41544497

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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A molecular basis for the diff ...... e spindle assembly checkpoint.

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A molecular basis for the diff ...... e spindle assembly checkpoint.

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A molecular basis for the diff ...... e spindle assembly checkpoint.

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A molecular basis for the diff ...... e spindle assembly checkpoint.

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Geert J P L Kops

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Ingrid Hoffmann

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Ivana Primorac

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Katharina Overlack

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Mathijs Vleugel

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Stefano Maffini

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Veronica Krenn

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P2860

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol.

Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint

Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction

The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

Bub1 regulates chromosome segregation in a kinetochore-independent manner

Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression

A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting

BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment

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e05269

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scholarly article

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10.7554/ELIFE.05269

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4

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Andrea Musacchio

Mathijs Vleugel

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2015-01-22T00:00:00Z

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271331473

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25611342

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4337726

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