Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease. - Test2 - elhamkhani - TriplyDB

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

http://www.wikidata.org/entity/Q42675021

about

Parkinson's disease: from monogenic forms to genetic susceptibility factors Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila Medical management of Parkinson's disease Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease LRRK2 as a Potential Genetic Modifier of Synucleinopathies: Interlacing the Two Major Genetic Factors of Parkinson's Disease The treatment of tremor R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.The curious case of phenocopies in families with genetic Parkinson's disease.Etiology and pathophysiology of frontotemporal dementia, Parkinson disease and Alzheimer disease: lessons from genetic studies.LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease Efficient allele-specific targeting of LRRK2 R1441 mutations mediated by RNAi.Parkinson's disease: Exit toxins, enter genetics Models for LRRK2-Linked Parkinsonism.Patterns of linkage disequilibrium of LRRK2 across different races: implications for genetic association studies.Lrrk2 p.Q1111H substitution and Parkinson's disease in Latin America.Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway Splicing: is there an alternative contribution to Parkinson's disease?G2019S LRRK2 mutation causing Parkinson's disease without Lewy bodies The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity The genetics of Parkinson's disease: progress and therapeutic implications Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.Genetics of Parkinson disease.Mutations in LRRK2 as a cause of Parkinson's disease.Progress in neuroprotection in Parkinson's disease.Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease.Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.Molecular pathogenesis of Parkinson disease: insights from genetic studies.Aberrant alternative splicing events in Parkinson's disease.Genetic basis of Parkinson's disease: inheritance, penetrance, and expression.Type II kinase inhibitors show an unexpected inhibition mode against Parkinson's disease-linked LRRK2 mutant G2019S.Leucine-Rich Repeat Kinase (LRRK2) Genetics and Parkinson's Disease.Genetics of Parkinson's disease and parkinsonism.High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts.LRRK2 dephosphorylation increases its ubiquitination.Connecting Ca2+ and lysosomes to Parkinson disease.

P2860

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P2860

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

http://www.wikidata.org/entity/Q42675021

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

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2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

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2006年论文

@zh-cn

name

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

@en

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

@nl

type

label

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

@en

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

@nl

prefLabel

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

@en

Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

@nl

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European Journal of Human Genetics

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Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

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Ben A Oostra

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Christan F Rohé

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Egberto Barbosa

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Emilia Martignoni

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Emiliana Fincati

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Erik J Simons

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Gianni Albani

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Giovanni Abbruzzese

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Giulio Riboldazzi

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Guido J Breedveld

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3

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14

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Stefano Goldwurm

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Parkinson's disease