Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.
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Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosomeAn interaction between human Sec63 and nucleoredoxin may provide the missing link between the SEC63 gene and polycystic liver diseaseSF1 and SF2 helicases: family mattersCryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feastDEAD/DExH-Box RNA Helicases in Selected Human ParasitesSki2-like RNA helicase structures: common themes and complex assembliesRNA helicases in splicingRNA helicase proteins as chaperones and remodelersStructural basis for the function of DEAH helicasesPrp43p contains a processive helicase structural architecture with a specific regulatory domainStructural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillanceMechanism for Aar2p function as a U5 snRNP assembly factorStructural Basis of Brr2-Prp8 Interactions and Implications for U5 snRNP Biogenesis and the Spliceosome Active SiteInhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 proteinThe DEAD-box helicase Ded1 from yeast is an mRNP cap-associated protein that shuttles between the cytoplasm and nucleus.The highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complexCofactor-dependent specificity of a DEAD-box protein.Spliceosome Structure and FunctionMutations in spliceosomal proteins and retina degenerationThe crystal structure of Mtr4 reveals a novel arch domain required for rRNA processingWinged helix domains with unknown function in Hel308 and related helicases.A novel missense SNRNP200 mutation associated with autosomal dominant retinitis pigmentosa in a Chinese family.The Mtr4 ratchet helix and arch domain both function to promote RNA unwindingBrr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding.Limited portability of G-patch domains in regulators of the Prp43 RNA helicase required for pre-mRNA splicing and ribosomal RNA maturation in Saccharomyces cerevisiae.BRR2a Affects Flowering Time via FLC SplicingFunctional roles of protein splicing factors.Mutations in Splicing Factor Genes Are a Major Cause of Autosomal Dominant Retinitis Pigmentosa in Belgian FamiliesBrr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioningSpliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2!Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs.The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine.Staying on message: ensuring fidelity in pre-mRNA splicing.Structural analyses of the pre-mRNA splicing machineryNovel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans.Spliceosome SNRNP200 Promotes Viral RNA Sensing and IRF3 Activation of Antiviral Response.Functions and regulation of the Brr2 RNA helicase during splicing.Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.
P2860
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P2860
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Common design principles in th ...... nd in the Hel308 DNA helicase.
@en
Common design principles in th ...... nd in the Hel308 DNA helicase.
@nl
type
label
Common design principles in th ...... nd in the Hel308 DNA helicase.
@en
Common design principles in th ...... nd in the Hel308 DNA helicase.
@nl
prefLabel
Common design principles in th ...... nd in the Hel308 DNA helicase.
@en
Common design principles in th ...... nd in the Hel308 DNA helicase.
@nl
P2093
P50
P921
P1433
P1476
Common design principles in th ...... nd in the Hel308 DNA helicase.
@en
P2093
Jerzy Orlowski
Patrizia Fabrizio
Sina Mozaffari Jovin
Vladimir Pena
P304
P356
10.1016/J.MOLCEL.2009.08.006
P577
2009-08-01T00:00:00Z