Mutual regulation between the spindle checkpoint and APC/C.
about
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingChemical Structure-Biological Activity Models for Pharmacophores' 3D-InteractionsFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisStructural analysis of human Cdc20 supports multisite degron recognition by APC/CInsights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 ComplexElectron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdownCryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin LigationChk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry.Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.Microtubule-dependent regulation of mitotic protein degradation.Construction of protein phosphorylation networks by data mining, text mining and ontology integration: analysis of the spindle checkpoint.Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.Cdc20 and securin overexpression predict short-term breast cancer survival.Identification of molecular pathways facilitating glioma cell invasion in situ.MDM4 overexpressed in acute myeloid leukemia patients with complex karyotype and wild-type TP53Structure-biological function relationship extended to mitotic arrest-deficient 2-like protein Mad2 native and mutants-new opportunity for genetic disorder control.Physiological change under OsHV-1 contamination in Pacific oyster Crassostrea gigas through massive mortality events on fields.The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.Targeting Cdc20 as a novel cancer therapeutic strategy.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisRole of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complexRanGTP aids anaphase entry through Ubr5-mediated protein turnover.Cyclin B3 controls anaphase onset independent of spindle assembly checkpoint in meiotic oocytes.Chlamydial infection induces host cytokinesis failure at abscission.Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylationMolecular characterization of the transition to mid-life in Caenorhabditis elegansTGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly.The composition, functions, and regulation of the budding yeast kinetochoreZfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes.Cks1: Structure, Emerging Roles and Implications in Multiple CancersSpindle assembly checkpoint: the third decade.Dissecting the NUP107 complex: multiple components and even more functions.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.A comprehensive analysis of CDC20 overexpression in common malignant tumors from multiple organs: its correlation with tumor grade and stage.Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma.Separase: Function Beyond Cohesion Cleavage and an Emerging Oncogene.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.
P2860
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P2860
Mutual regulation between the spindle checkpoint and APC/C.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mutual regulation between the spindle checkpoint and APC/C.
@ast
Mutual regulation between the spindle checkpoint and APC/C.
@en
type
label
Mutual regulation between the spindle checkpoint and APC/C.
@ast
Mutual regulation between the spindle checkpoint and APC/C.
@en
prefLabel
Mutual regulation between the spindle checkpoint and APC/C.
@ast
Mutual regulation between the spindle checkpoint and APC/C.
@en
P2860
P1476
Mutual regulation between the spindle checkpoint and APC/C.
@en
P2093
Hongtao Yu
Soonjoung Kim
P2860
P304
P356
10.1016/J.SEMCDB.2011.03.008
P577
2011-03-23T00:00:00Z