{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice
about
Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acidsp66 -MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complexMi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic miceA cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathiesPositive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production.A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblastsDesign of embedded chimeric peptide nucleic acids that efficiently enter and accurately reactivate gene expression in vivoFunctional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2CβTriplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells.Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells.Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders.Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site.siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures.Induction of Fetal Hemoglobin In Vivo Mediated by a Synthetic γ-Globin Zinc Finger Activator.An Introduction to Erythropoiesis Approaches.
P2860
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P2860
{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@ast
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en-gb
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@nl
type
label
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@ast
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en-gb
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@nl
prefLabel
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@ast
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en-gb
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@nl
P2093
P2860
P356
P1476
{gamma}-Globin gene expression ...... e ({beta}-YAC) transgenic mice
@en
P2093
Anna L Bomhoff
C Anthony Blau
Carlos F Barbas
Kenneth R Peterson
Patrick A Navas
Renee Neades
P2860
P304
P356
10.1074/JBC.M504402200
P407
P577
2005-11-04T00:00:00Z