Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
about
Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic miceTissue-Specific Replicating Capacity of a Chimeric Poliovirus That Carries the Internal Ribosome Entry Site of Hepatitis C Virus in a New Mouse Model Transgenic for the Human Poliovirus ReceptorRecruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.Animal models of β-hemoglobinopathies: utility and limitationsMi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic miceA cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathiesT to C substitution at -175 or -173 of the gamma-globin promoter affects GATA-1 and Oct-1 binding in vitro differently but can independently reproduce the hereditary persistence of fetal hemoglobin phenotype in transgenic miceTransgenic rescue of SF-1-null mice.Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.Investigations of a human embryonic globin gene silencing element using YAC transgenic mice.Purification and identification of proteins that bind to the hereditary persistence of fetal hemoglobin -198 mutation in the gamma-globin gene promoterControl of globin gene expression during development and erythroid differentiationAdult stage gamma-globin silencing is mediated by a promoter direct repeat element.Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletionSubstitution of the human beta-spectrin promoter for the human agamma-globin promoter prevents silencing of a linked human beta-globin gene in transgenic miceMutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a)Genome architecture of the human beta-globin locus affects developmental regulation of gene expressionThe minimal promoter plays a major role in silencing of the galago gamma-globin gene in adult erythropoiesis.Erythropoiesis: development and differentiation.Position-independent expression of a human nerve growth factor-luciferase reporter gene cloned on a yeast artificial chromosome vector.Autonomous silencing as well as competition controls gamma-globin gene expression during development.A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes.Sequences in the (A)gamma-delta intergenic region are not required for stage-specific regulation of the human beta-globin gene locusA FTZ-F1-containing yeast artificial chromosome recapitulates expression of steroidogenic factor 1 in vivo.Distal regulatory elements are required for Fshr expression, in vivo.Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis.Regulation of human fetal hemoglobin: new players, new complexities.LCR 5' hypersensitive site specificity for globin gene activation within the active chromatin hub.High levels of human gamma-globin gene expression in adult mice carrying a transgene of deletion-type hereditary persistence of fetal hemoglobinTriplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.Preclinical transfusion-dependent humanized mouse model of beta thalassemia major.Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site.Engineering EGFP reporter constructs into a 200 kb human beta-globin BAC clone using GET Recombination.Analysis of the mechanism of action of non-deletion hereditary persistence of fetal hemoglobin mutants in transgenic mice.A dicistronic construct allows easy detection of human CFTR expression from YAC DNA in human cells.Factor binding to the human gamma-globin gene distal CCAAT site: candidates for repression of the normal gene or activation of HPFH mutants.A locus control region at -12 kb of the tyrosinase gene.Activation of the rat follicle-stimulating hormone receptor promoter by steroidogenic factor 1 is blocked by protein kinase a and requires upstream stimulatory factor binding to a proximal E box element.
P2860
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P2860
Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Use of yeast artificial chromo ...... globin developmental mutants.
@ast
Use of yeast artificial chromo ...... globin developmental mutants.
@en
Use of yeast artificial chromosomes
@nl
type
label
Use of yeast artificial chromo ...... globin developmental mutants.
@ast
Use of yeast artificial chromo ...... globin developmental mutants.
@en
Use of yeast artificial chromosomes
@nl
prefLabel
Use of yeast artificial chromo ...... globin developmental mutants.
@ast
Use of yeast artificial chromo ...... globin developmental mutants.
@en
Use of yeast artificial chromosomes
@nl
P2093
P2860
P356
P1476
Use of yeast artificial chromo ...... globin developmental mutants.
@en
P2093
E J Norton
G Stamatoyannopoulos
K R Peterson
T Furukawa
T G Kimbrough
P2860
P304
P356
10.1073/PNAS.92.12.5655
P407
P577
1995-06-01T00:00:00Z