Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues
about
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and releaseInsights into open/closed conformations of the catalytically active human guanylate kinase as investigated by small-angle X-ray scattering.Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine.Redesigning human 2'-deoxycytidine kinase enantioselectivity for L-nucleoside analogues as reporters in positron emission tomographyStructure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.Cell fate control gene therapy based on engineered variants of human deoxycytidine kinaseA Positive Selection for Nucleoside Kinases in E. coliPost-transcriptional controls by ribonucleoprotein complexes in the acquisition of drug resistance.Comparative Analysis of Human Nucleoside Kinase-Based Reporter Systems for PET Imaging.Understanding the role of structural integrity and differential expression of integrin profiling to identify potential therapeutic targets in breast cancer.Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer.Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase.Photo-electrochemical Bioanalysis of Guanosine Monophosphate Using Coupled Enzymatic Reactions at a CdS/ZnS Quantum Dot Electrode.
P2860
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P2860
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural and kinetic charact ...... tidine and thymidine analogues
@ast
Structural and kinetic charact ...... tidine and thymidine analogues
@en
Structural and kinetic charact ...... tidine and thymidine analogues
@nl
type
label
Structural and kinetic charact ...... tidine and thymidine analogues
@ast
Structural and kinetic charact ...... tidine and thymidine analogues
@en
Structural and kinetic charact ...... tidine and thymidine analogues
@nl
altLabel
Structural and Kinetic Charact ...... idine and Thymidine Analogues,
@en
prefLabel
Structural and kinetic charact ...... tidine and thymidine analogues
@ast
Structural and kinetic charact ...... tidine and thymidine analogues
@en
Structural and kinetic charact ...... tidine and thymidine analogues
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structural and kinetic charact ...... tidine and thymidine analogues
@en
P2093
Manfred Konrad
Saugata Hazra
Stephan Ort
P2860
P304
P3181
P356
10.1021/BI100839E
P407
P50
P577
2010-08-10T00:00:00Z