The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
about
Regulation of FynT function by dual domain docking on PAG/CbpThe adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factorsH3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependencyLinker length dependent binding of a focal adhesion kinase derived peptide to the Src SH3-SH2 domainsMeasurement of the formation of complexes in tyrosine kinase-mediated signal transductionThe high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complexThe high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation MechanismRigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor TriggeringHigh-resolution crystal structure of spectrin SH3 domain fused with a proline-rich peptideFAK dimerization controls its kinase-dependent functions at focal adhesionsSuperbinder SH2 domains act as antagonists of cell signalingTwo Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated CortactinDynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its ActivityMolecular dynamics and protein function.SH3 domains: modules of protein-protein interactions.Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitmentTwo-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-capDancing retro: solution structure and micelle interactions of the retro-SH3-domain, retro-SHH-'Bergerac'.Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains.Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase.Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn.Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structureOn the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases.Structure and regulation of Src family kinases.A binding event converted into a folding event.Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes.Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.How focal adhesion kinase achieves regulation by linking ligand binding, localization and actionSH2 domains: modulators of nonreceptor tyrosine kinase activity.How to find a leucine in a haystack? Structure, ligand recognition and regulation of leucine-aspartic acid (LD) motifs.N-acyl-3,5-bis(arylidene)-4-piperidones and related compounds which stimulate fyn kinase.Purification, crystallization and preliminary X-ray diffraction analysis of the Fyn SH2 domain and its complex with a phosphotyrosine peptide.1H, 13C and 15N backbone and side-chain chemical shift assignment of the Fyn SH2 domain and its complex with a phosphotyrosine peptide.Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain.Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development.
P2860
Q24302122-E386AFB9-8E41-44F9-9095-1E3CD3653E8FQ24304594-9E7E278F-2D47-410C-B122-56558BA972CEQ24322697-C7057E7F-79AD-4183-B667-0A795C8FF745Q24338375-B8D81955-4303-4100-BEE9-D408DC8DE1D4Q24654723-84FD0B0E-39ED-4293-A827-E7DA463A6698Q27643727-622F6051-BA4C-4C1C-B22A-7DF825DC6592Q27644350-B5239135-BA5D-4F5E-81D0-90759848CE6CQ27664248-212BC4B1-911E-4CF8-92E1-6E82627C6B1FQ27666303-DAEFB112-8514-4ECF-A195-A3E3C1B30F92Q27675446-1634BC60-7E30-4A78-B988-E04ED62D6470Q27681534-AC040DCD-E6A7-4CE5-8617-9C062DDAAC02Q27682496-FEE524A5-C85F-403F-B2E4-297B4EDE5F85Q27684053-2CC7A43C-16A9-4EF8-9D67-FD1414DE2A14Q27728152-E9D9B64C-8AC1-4ABB-8578-F811E8583141Q28248486-151929E1-FDDD-4445-86A0-BBE7C18221E7Q30008731-B4C67F52-9C16-44DB-8BEE-994B3938C82AQ30009331-73B0F2DE-D0B3-466D-BD1C-671ACF2CC480Q30009582-6BE8EB95-CAAC-4B23-AE49-99CE1AFDFCC0Q30009894-0F33D246-6AC1-48A0-BE45-E8AE9D17EAEAQ30010103-0843C0A4-B2FB-47DC-A425-8F7304DE28D3Q30155944-090E93F2-C7F8-40CB-8B44-A6977C281DE2Q30157097-C39E67EC-E606-4B1A-A679-C1D87BDDB1C9Q30157500-F7248EB5-41C4-4A10-9AAD-92449A460169Q30157892-CE3F5354-EEC0-4877-AC01-C50EEBCA838AQ30160827-8F2009EB-D318-40E3-AEBC-1116AA7E94EAQ30164441-F6857CD8-1D76-4356-B86F-5C3B0FB507E2Q33215754-83B48754-095B-4E94-AB95-F56E9E69647BQ33988602-B5E3499D-B1D3-4798-B7FF-83CDDCD4E7F4Q34504260-5DAFBC52-1DC9-4A9F-A2CB-A053C2285F9AQ35597027-9B0CA554-355A-4C76-9B72-CEC8A0833832Q37635474-11CEFDDC-52D6-4E33-94D8-FA3FD2C9170EQ38215562-D0ADA718-1981-485F-A35B-E62AD06B24ACQ40175455-F638BB02-EF4F-4B63-BB09-AE8991E49988Q41931642-726C93FC-1F7D-44AB-8FDF-B879EDAB9DBBQ44436279-F62D3CA4-CA11-43E9-A156-025D334F4CA4Q48869823-69EFF332-E185-4AA7-AF97-37ED90931E88Q54976490-992ECB50-D149-418D-BCD6-B03E70539C49
P2860
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@ast
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@en
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@nl
type
label
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@ast
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@en
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@nl
prefLabel
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@ast
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@en
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@nl
P2093
P2860
P50
P356
P1476
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases
@en
P2093
P2860
P304
17199-17205
P356
10.1074/JBC.M011185200
P407
P577
2001-02-02T00:00:00Z