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Antioxidants of Edible MushroomsPerfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma InactivationSelective Sirt2 inhibition by ligand-induced rearrangement of the active site.Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.Propofol inhibits SIRT2 deacetylase through a conformation-specific, allosteric site.Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studiesStructural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrolFinding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 InhibitorDeacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia.Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADHN-Acylethanolamines Bind to SIRT6SIRT1 inhibits EV71 genome replication and RNA translation by interfering with the viral polymerase and 5'UTR RNAUnreported intrinsic disorder in proteins: Building connections to the literature on IDPs.Synthesis and Evaluation of New Benzodioxole- Based Thiosemicarbazone Derivatives as Potential Antitumor Agents.Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking.The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.Sirtuin 5: a review of structure, known inhibitors and clues for developing new inhibitors.Efficient demyristoylase activity of SIRT2 revealed by kinetic and structural studies.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Chemical and structural biology of protein lysine deacetylasesJamming up the "β-staple": regulation of SIRT1 activity by its C-terminal regulatory segment (CTR).Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by Cysteine S-Nitrosation.Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription.From the Cover: l-Carnitine via PPARγ- and Sirt1-Dependent Mechanisms Attenuates Epithelial-Mesenchymal Transition and Renal Fibrosis Caused by Perfluorooctanesulfonate.Directed evolution of SIRT6 for improved deacylation and glucose homeostasis maintenance.The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design.Anti-Oxidant and Anti-Inflammatory Activity of Ketogenic Diet: New Perspectives for Neuroprotection in Alzheimer's Disease.Polypharmacology or Promiscuity? Structural Interactions of Resveratrol With Its Bandwagon of TargetsSirtuins in Neuroendocrine Regulation and Neurological DiseasesMetformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structural and Functional Analysis of Human SIRT1
@ast
Structural and Functional Analysis of Human SIRT1
@en
Structural and Functional Analysis of Human SIRT1
@nl
type
label
Structural and Functional Analysis of Human SIRT1
@ast
Structural and Functional Analysis of Human SIRT1
@en
Structural and Functional Analysis of Human SIRT1
@nl
prefLabel
Structural and Functional Analysis of Human SIRT1
@ast
Structural and Functional Analysis of Human SIRT1
@en
Structural and Functional Analysis of Human SIRT1
@nl
P2093
P2860
P3181
P1476
Structural and Functional Analysis of Human SIRT1
@en
P2093
Andrew M Davenport
André Hoelz
Ferdinand M Huber
P2860
P304
P3181
P356
10.1016/J.JMB.2013.10.009
P407
P577
2014-02-06T00:00:00Z