Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis
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ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stabilityNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activityProstaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activationAkt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.The Ubiquitination of NF-κB Subunits in the Control of TranscriptionThe Regulation of NF-κB Subunits by PhosphorylationNF-κB, the first quarter-century: remarkable progress and outstanding questionsbetaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signalingAssociation of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinasesRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseTomato TFT1 is required for PAMP-triggered immunity and mutations that prevent T3S effector XopN from binding to TFT1 attenuate Xanthomonas virulenceABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesPTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit.Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domainNfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms.The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylationCaspase-mediated processing of the Drosophila NF-kappaB factor Relish.Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease.NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.Dual function of an Arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression.Functions of NF-kappaB1 and NF-kappaB2 in immune cell biologyFunctions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice.Coordinate regulation of TPL-2 and NF-κB signaling in macrophages by NF-κB1 p105.IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400A comprehensive map of the toll-like receptor signaling network.Coordinating TLR-activated signaling pathways in cells of the immune system.The ubiquitin-proteasome system and activation of NF-κB: involvement of the ubiquitin ligase KPC1 in p105 processing and tumor suppressionQuantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide.Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cellsConstitutive renal Rel/nuclear factor-κB expression in Lewis polycystic kidney disease rats.PAFR activation of NF-κB p65 or p105 precursor dictates pro- and anti-inflammatory responses during TLR activation in murine macrophagesLipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.IκB kinase regulation of the TPL-2/ERK MAPK pathway.NFKB1: a suppressor of inflammation, ageing and cancer.Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma.Variation in positive selection in termite GNBPs and Relish.
P2860
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P2860
Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis
description
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/06/22)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/06/22)
@nl
наукова стаття, опублікована в червні 2001
@uk
name
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@ast
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@en
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@nl
type
label
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@ast
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@en
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@nl
prefLabel
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@ast
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@en
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@nl
P2093
P3181
P356
P1476
Direct phosphorylation of NF-k ...... ignal-induced p105 proteolysis
@en
P2093
A. Salmerón
P304
22215–22222
P3181
P356
10.1074/JBC.M101754200
P407
P577
2001-06-22T00:00:00Z