Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.
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Regulation of miRNA transcription in macrophages in response to Candida albicansThe tyrosine kinase Syk regulates TPL2 activation signalsProstaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activationp53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loopLoss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesisInterleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinaseUbiquitin signaling in immune responsesNF-κB, the first quarter-century: remarkable progress and outstanding questionsTumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerTumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8+ T Cell Responses and Protects against Influenza VirusRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseThe protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs)ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesTpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.Pulmonary hypertension and vasculopathy in incontinentia pigmenti: a case report.A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinasesPhosphorylation at Thr-290 regulates Tpl2 binding to NF-kappaB1/p105 and Tpl2 activation and degradation by lipopolysaccharide.TNF and MAP kinase signalling pathways.TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling.Mechanisms of action and clinical application of macrolides as immunomodulatory medications.Tumor necrosis factor α stimulates endothelin-1 synthesis in rat hepatic stellate cells in hepatic wound healing through a novel IKK/JNK pathway.Nfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms.IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activationInterleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose.The IκB kinase complex in NF-κB regulation and beyond.Genome-scale identification and characterization of moonlighting proteins.Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis.IKK biology.p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activationCoordinate regulation of TPL-2 and NF-κB signaling in macrophages by NF-κB1 p105.Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages.IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.Attenuation of inflammatory mediator production by the NF-κB member RelB is mediated by microRNA-146a in lung fibroblasts.
P2860
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P2860
Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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2004年學術文章
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2004年學術文章
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name
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@en
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@nl
type
label
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@en
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@nl
prefLabel
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@en
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@nl
P2093
P2860
P1476
Lipopolysaccharide activation ...... roteolysis of NF-kappaB1 p105.
@en
P2093
P2860
P304
P356
10.1128/MCB.24.21.9658-9667.2004
P407
P577
2004-11-01T00:00:00Z