about
A molecular marker of artemisinin-resistant Plasmodium falciparum malariaMolecular basis of electrophilic and oxidative defense: promises and perils of Nrf2Role of Nrf2 in oxidative stress and toxicityStructure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingMutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralizationUbiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathwayCysteine-based regulation of the CUL3 adaptor protein Keap1Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant responseAdvances in mechanisms of anti-oxidationSequence and structural analysis of BTB domain proteinsThe Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseasesSialic acid mutarotation is catalyzed by the Escherichia coli beta-propeller protein YjhTStructural analysis of the complex of Keap1 with a prothymosin α peptideStructural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4Novel -Propeller of the BTB-Kelch Protein Krp1 Provides a Binding Site for Lasp-1 That Is Necessary for Pseudopodial ExtensionStructural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin LigasesCrystal-contact engineering to obtain a crystal form of the Kelch domain of human Keap1 suitable for ligand-soaking experimentsStructural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulationThe crystal structure of the thiocyanate-forming protein from Thlaspi arvense, a kelch protein involved in glucosinolate breakdownSaccharomyces cerevisiae Kelch proteins and Bud14 protein form a stable 520-kDa formin regulatory complex that controls actin cable assembly and cell morphogenesisDiscovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agentsMechanistic studies of the Nrf2-Keap1 signaling pathwayCellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disordersStress-activated cap'n'collar transcription factors in aging and human diseaseSmall molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agentsDimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress ResponsesRedox homeostasis: the linchpin in stem cell self-renewal and differentiationInteraction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosisKeap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition modelPlasmodium falciparum Resistance to Artemisinin Derivatives and Piperaquine: A Major Challenge for Malaria Elimination in Cambodia.Prospective type 1 and type 2 disulfides of Keap1 protein.Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast.Detection of autoantibodies to the BTB-kelch protein KLHL7 in cancer sera.Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domainsElectrophilic tuning of the chemoprotective natural product sulforaphane.Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomasA comprehensive analysis of interaction and localization of Arabidopsis SKP1-like (ASK) and F-box (FBX) proteins.The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.Structural assembly of cullin-RING ubiquitin ligase complexes.Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation
P2860
Q22061872-6DF4ADD7-826E-4186-8A4E-C3FC6D7F0A62Q23919668-0137E535-7AF3-4167-B502-E25A3109596EQ23919669-6261434E-5C03-4F27-AB68-4BD1C6F02F3CQ24298930-673C82FA-B64B-45DD-9674-6D8CE5253387Q24300813-6F2D9FC3-0955-443A-BB9B-9E0F8463C539Q24306215-65C70914-7E65-4D59-ADFD-AC4A51A0A918Q24629359-80A3E67F-4587-4BFB-B2D7-CFF3EE497800Q24646029-0ECA08ED-B462-40C9-8CBB-FE07CDF28E2DQ24704009-A39B554F-06FB-4EB5-9D87-A339845981F9Q24812693-3C50FFF1-031F-4DC8-9259-8C1248DA2625Q26822972-962E07E6-C76B-4347-BCDC-36A45EC084FCQ27649228-EB2679B8-7FB7-4A96-ABC3-25C90AB08E29Q27650252-FCF43AC8-4627-4B84-A783-2D85A1E708FAQ27654126-2F5A0368-84A7-4B1B-856A-9805007797AFQ27657284-65DB7A4B-ACEC-4564-AFE8-8FD7A283F65BQ27675990-E5C39A53-B225-4929-A76D-6827FD00ABFFQ27678396-2C8557B8-094B-4291-8492-8F73C1623F6DQ27682289-93282668-453C-4FF7-AF99-934E879CBB8BQ27701775-1FD69CDA-1A08-4754-A4F5-54C314125935Q27935950-F88BD0CF-FFAA-497B-94DD-F7980A7FEA3BQ28085561-AD3AE644-B0AA-4107-B2EB-10F575777F15Q28277182-A8281334-572E-4484-9D42-1461803FE9F2Q28384232-71F39046-1E91-45BC-9B77-220691769D41Q28384783-D2D095B2-680D-4F5F-8D20-161029C5C4F9Q28386244-2D8F650C-69D1-4DD4-8956-2150D26C11B2Q28388484-96802D99-8CF9-474A-B779-8ABBA16C2FA2Q28396335-C934EC5C-34E4-4C75-89D3-1271F3B7A298Q28591483-68C84CC9-31EF-46E4-9ECF-C6D280075D7EQ28910182-1444F56B-1F21-4AF1-B2C9-75A3417A453AQ30240158-CDF003FA-B000-489E-9857-240959726228Q30371642-163126AB-3E75-49D4-A627-AAC0B1E0FFCDQ30476340-FC824645-6CBC-46AE-8220-14CFBCC4436FQ33254440-AA1DD4A5-9321-468C-9CD4-AED38EC122BDQ33734064-A5104C1A-794E-4D8D-8A1B-4C937C3F6FD3Q34006681-7F32A617-2F7B-4779-9EB3-AF9DB5AF4148Q34393793-6687C776-2A1F-45A0-98A6-26546D719909Q34482944-8ACED4A4-663C-4505-858F-D671E1CAF606Q34682265-D4ED4D23-3480-474D-8474-FBCC53E50B13Q34762436-A0D3DE90-11A1-4572-B97F-63DB8A3595BDQ34997448-4B96EB05-E096-45DA-8103-D23C3101DE32
P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Crystal structure of the Kelch domain of human Keap1
@ast
Crystal structure of the Kelch domain of human Keap1
@en
Crystal structure of the Kelch domain of human Keap1
@nl
type
label
Crystal structure of the Kelch domain of human Keap1
@ast
Crystal structure of the Kelch domain of human Keap1
@en
Crystal structure of the Kelch domain of human Keap1
@nl
prefLabel
Crystal structure of the Kelch domain of human Keap1
@ast
Crystal structure of the Kelch domain of human Keap1
@en
Crystal structure of the Kelch domain of human Keap1
@nl
P2093
P2860
P356
P1476
Crystal structure of the Kelch domain of human Keap1
@en
P2093
Donna Zhang
Lesa J Beamer
Mark Hannink
P2860
P304
P356
10.1074/JBC.M410073200
P407
P577
2004-12-24T00:00:00Z