The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
about
Defective development of secretory neurones in the hypothalamus of Arnt2-knockout miceMore targets, more pathways and more clues for mutant p53.Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.Chronic cyclic bladder over distention up-regulates hypoxia dependent pathwaysLoss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growthMice with inactivation of aryl hydrocarbon receptor-interacting protein (Aip) display complete penetrance of pituitary adenomas with aberrant ARNT expressionIndividual variation of the genetic response to bisphenol a in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patientsAltered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs.HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition.O2 regulates stem cells through Wnt/β-catenin signalling.Genetic variant rs17225178 in the ARNT2 gene is associated with Asperger SyndromeMultiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt.Cellular response to tissue hypoxia and its involvement in disease progression.The role of hypoxia inducible factor-1 in cell metabolism--a possible target in cancer therapy.Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiationThe role of hypoxia-inducible factors in tumorigenesis.STAT3 targets suggest mechanisms of aggressive tumorigenesis in diffuse large B-cell lymphoma.Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation.Transcript variations, phylogenetic tree and chromosomal localization of porcine aryl hydrocarbon receptor (AhR) and AhR nuclear translocator (ARNT) genes.Downregulation of ARNT2 promotes tumor growth and predicts poor prognosis in human hepatocellular carcinoma.siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells.Aryl hydrocarbon nuclear translocator (ARNT) promotes oxygen-independent stabilization of hypoxia-inducible factor-1alpha by modulating an Hsp90-dependent regulatory pathway.Identification of target genes for EWS/ATF-1 chimeric transcription factor.Identification and functional characterization of hypoxia-inducible factor 2alpha from the estuarine teleost, Fundulus heteroclitus: interaction of HIF-2alpha with two ARNT2 splice variants.p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species.Hippocampal expression of aryl hydrocarbon receptor nuclear translocator 2 and neuronal PAS domain protein 4 in a rat model of depression.Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness.Hypoxia, HIFs, and cardiovascular development.A search for genes that may confer divergent morphology and function in the carotid body between two strains of mice.Genes Related to Autistic Traits and EmpathyIntegrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia
P2860
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P2860
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/24)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/24)
@nl
наукова стаття, опублікована в червні 2000
@uk
مقالة علمية (نشرت في 24-6-2000)
@ar
name
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@ast
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@en
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@nl
type
label
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@ast
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@en
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@nl
prefLabel
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@ast
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@en
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@nl
P2093
P356
P1476
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia
@en
P2093
A. M. Arsham
E. Maltepe
J. R. Brorson
M. C. Simon
P304
P356
10.1006/BBRC.2000.2928
P407
P577
2000-06-24T00:00:00Z