Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
about
Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5Raf family kinases: old dogs have learned new tricksPHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in miceRASSF2 associates with and stabilizes the proapoptotic kinase MST2Protein phosphatase 5 protects neurons against amyloid-beta toxicityTargeting protein serine/threonine phosphatases for drug developmentJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsDynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancyHigh yield expression of serine/threonine protein phosphatase type 5, and a fluorescent assay suitable for use in the detection of catalytic inhibitors.A proteomic study of cMyc improvement of CHO culture.Decreased ERK and JNK signaling contribute to gene overexpression in "senescent" CD4+CD28- T cells through epigenetic mechanismsNovel Ser/Thr protein phosphatase 5 (PP5) regulated targets during DNA damage identified by proteomics analysis.NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction.A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing.Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cellsFormation of intracellular concentration landscapes by multisite protein modification.Nanotopographical control of stem cell differentiation.Differential activation of Toll-like receptor-mediated apoptosis induced by hypoxiaDisruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1).Scaffold proteins confer diverse regulatory properties to protein kinase cascades.Estradiol and Estrogen Receptor Agonists Oppose Oncogenic Actions of Leptin in HepG2 CellsRaf kinases: function, regulation and role in human cancer.Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivoRole of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening.Knockdown of protein phosphatase 5 inhibits ovarian cancer growth in vitro.The role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancerG protein regulation of MAPK networks.Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancerHsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrestHeat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells.Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.Mechanistic principles of RAF kinase signaling.Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.Protein phosphatases in pancreatic islets."RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway.Targeting Hsp90 and its co-chaperones to treat Alzheimer's diseaseThe muscle-specific chaperone protein melusin is a potent cardioprotective agent.
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P2860
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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im September 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@ast
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@en
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@nl
type
label
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@ast
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@en
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@nl
prefLabel
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@ast
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@en
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@nl
P2860
P50
P3181
P356
P1433
P1476
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
@en
P2093
Amardeep S. Dhillon
G. Joan Grindlay
P2860
P2888
P304
P3181
P356
10.1038/NCB1465
P577
2006-09-01T00:00:00Z
P5875
P6179
1030229787