The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity
about
Dysregulation of histone acetyltransferases and deacetylases in cardiovascular diseasesSIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1Epigenetic abnormalities in cardiac hypertrophy and heart failureThe emerging role of epigenetics in cardiovascular diseaseEpigenetic mechanisms underlying cardiac degeneration and regenerationProtein lysine acetylation by p300/CBPModulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardinCurcumin prevents and reverses murine cardiac hypertrophyThe transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortinHistone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart developmentp38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair.A ternary complex of transcription factors, Nishéd and NFATc4, and co-activator p300 bound to an intronic sequence, intronic regulatory element, is pivotal for the up-regulation of myosin light chain-2v gene in cardiac hypertrophy.Differential functions of genes regulated by VEGF-NFATc1 signaling pathway in the migration of pulmonary valve endothelial cellsDecoding the complex genetic causes of heart diseases using systems biologyRole of cyclic AMP-dependent kinase response element-binding protein in recombinant adeno-associated virus-mediated transduction of heart muscle cells.Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells.Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive ratsCardio-Oncology: Cancer Therapy-related Cardiovascular Complications in a Molecular Targeted Era: New Concepts and Perspectives.Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy.Non-histone lysine acetylated proteins in heart failureEpigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytesEpigenetic mechanisms in heart failure pathogenesisCurcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription.Understanding the acetylome: translating targeted proteomics into meaningful physiologyCalcium-mediated histone modifications regulate alternative splicing in cardiomyocytes.Epigenetics and cardiovascular disease.Chromatin remodeling in cardiovascular development and physiology.Readers, writers, and erasers: chromatin as the whiteboard of heart diseaseRe-employment of developmental transcription factors in adult heart diseaseNanocurcumin Prevents Hypoxia Induced Stress in Primary Human Ventricular Cardiomyocytes by Maintaining Mitochondrial Homeostasis.VCNet: Vector based gene Co-expression Network construction and its application to RNA-seq data.Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses.Genetics and epigenetics of arrhythmia and heart failure.Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern?Epigenetics and chromatin remodeling in adult cardiomyopathy.Matrix revisited: mechanisms linking energy substrate metabolism to the function of the heart.Chromatin modifications remodel cardiac gene expression.
P2860
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P2860
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/02/28)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/28)
@nl
наукова стаття, опублікована в лютому 2003
@uk
name
The transcriptional co-activat ...... one acetyltransferase activity
@ast
The transcriptional co-activat ...... one acetyltransferase activity
@en
The transcriptional co-activat ...... one acetyltransferase activity
@nl
type
label
The transcriptional co-activat ...... one acetyltransferase activity
@ast
The transcriptional co-activat ...... one acetyltransferase activity
@en
The transcriptional co-activat ...... one acetyltransferase activity
@nl
prefLabel
The transcriptional co-activat ...... one acetyltransferase activity
@ast
The transcriptional co-activat ...... one acetyltransferase activity
@en
The transcriptional co-activat ...... one acetyltransferase activity
@nl
P2093
P2860
P356
P1476
The transcriptional co-activat ...... one acetyltransferase activity
@en
P2093
David S Latchman
Elen Jazrawi
Rosalind J Gusterson
P2860
P304
P356
10.1074/JBC.M211762200
P407
P577
2002-12-10T00:00:00Z