Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
about
SPAK, a STE20/SPS1-related kinase that activates the p38 pathwayCloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing propertiesCoexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brainCloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoformPASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinaseIdentification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lensesThe WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinasesThe Ste20 kinases Ste20-related proline-alanine-rich kinase and oxidative-stress response 1 regulate NKCC1 function in sensory neuronsIdentification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinaseCation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)Glial ensheathment of peripheral axons in Drosophila.Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis.Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia.STE20/SPS1-related proline/alanine-rich kinase (SPAK) is critical for sodium reabsorption in isolated, perfused thick ascending limb.Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.The role of Na-K-Cl co-transporter in cerebral ischemia.Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channelSPAK differentially mediates vasopressin effects on sodium cotransporters.Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans.SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway.Ste20-related proline/alanine-rich kinase: a novel regulator of intestinal inflammation.OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis.Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.PKC-θ is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection.Emerging role of WNK1 in pathologic central nervous system signaling.Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport.Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.Identification of p21-activated kinase specificity determinants in budding yeast: a single amino acid substitution imparts Ste20 specificity to Cla4.PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells.Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses.Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans.SPAK-sensitive regulation of glucose transporter SGLT1.
P2860
Q24290222-4D3C62FA-6B9A-4B2D-A08F-562F28535316Q24291998-88A1C7C0-425C-450E-8F0F-1D8B4688A179Q24647954-7CC58F59-9CE2-4263-BE02-DDF765B08DE9Q24672948-76ACF870-A172-4A3D-AB3F-11116F6A9287Q28116210-CBA420A4-C9D6-4313-8BA5-56C5B1492425Q28210550-76DD905B-D095-4ACF-B7AE-60C8D11BEE0DQ28581906-E9BD695A-DC7E-49B3-9A48-46627C13A510Q28583124-62D79E0F-6273-4E15-8EBA-2898AE2C6C68Q28584102-B99BF326-8BCD-47A6-BB3C-70091439F72FQ28587982-B6FD8589-587B-4FC4-A850-FCD8DFBDB37CQ28593751-6DBB9FAD-61F2-4103-AAB6-6CBE430E698FQ33697461-FE3D695E-5F41-4CE3-9BC9-229F27B28B97Q33797449-3916408B-5874-4517-BDF2-5C9EB920EBEEQ34301998-8A5E5010-F321-4EFC-9034-9E808950743DQ34457030-B7CEF3F4-D5B3-4D29-AABD-B47F2569F1C2Q34462143-1811B777-EEE9-4C59-AB7D-FBDF61B9B512Q35138491-BCF65792-9758-486C-A86C-8D65DD420585Q35900778-455ACD0B-D376-4B15-8B57-28B7766A5016Q36104047-368ACF41-978D-4DB4-A68D-F3DDDCE0E761Q36380595-C49AEF0F-905F-42B6-BFAE-9BA4094AEDEBQ36412608-BC5A6624-5F3A-4FB8-9A7D-9D39EBB19063Q36638355-3C2D471F-79F8-4872-8767-345B9391555FQ36974966-085983B3-BA34-4711-88B0-DD2C9379CA17Q37259298-ECD8BDAE-4746-4F2C-8CF4-DAAFA4FA2DAEQ37318058-E1FA51AA-7ED1-47A0-87DB-F67E37ABBA9BQ37419158-967E7539-39EC-4170-9CE5-9729EF3F62F6Q37773549-5987B000-BCD3-482D-AE9E-7117D322599CQ37798037-EBB0D5C4-0886-4526-B3FF-3C98B114469FQ38247943-2135DC52-3EA2-4967-8BFB-5B2FF98AAEEDQ39415845-2578C629-D0AD-4271-8CD2-48D758D3CFECQ39698346-3A034EA3-10F2-4951-B580-BFB43CF2136AQ39740330-B251834E-BE45-4382-B47F-54A2E5AD18C1Q39972775-518C0CD1-9A7D-4B07-900E-7E23E1FFA1E4Q42479166-6AFAAF0D-D543-4B8B-9E98-1BD2455F9E07Q42803978-B5169992-297C-4787-8075-CDA92185AD99Q47068785-8BB7DC7A-7C88-45AF-BE84-F97A85379368Q48595475-B1AF0013-375F-47DC-BEE6-C77E78271F2D
P2860
Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
description
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Juli 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/07/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/07/15)
@nl
наукова стаття, опублікована в липні 1998
@uk
مقالة علمية (نشرت في 15-7-1998)
@ar
name
Molecular cloning and characte ...... ons and transporting epithelia
@ast
Molecular cloning and characte ...... ons and transporting epithelia
@en
Molecular cloning and characte ...... ons and transporting epithelia
@nl
type
label
Molecular cloning and characte ...... ons and transporting epithelia
@ast
Molecular cloning and characte ...... ons and transporting epithelia
@en
Molecular cloning and characte ...... ons and transporting epithelia
@nl
prefLabel
Molecular cloning and characte ...... ons and transporting epithelia
@ast
Molecular cloning and characte ...... ons and transporting epithelia
@en
Molecular cloning and characte ...... ons and transporting epithelia
@nl
P2093
P356
P1476
Molecular cloning and characte ...... ons and transporting epithelia
@en
P2093
T. Kayahara
T. Tsutsumi
P304
P356
10.1006/ABBI.1998.0736
P407
P577
1998-07-15T00:00:00Z