Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
about
Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro.Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55Differential regulation of TCR-mediated gene transcription by Vav family membersAssociation of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transductionFunctional roles of Syk in macrophage-mediated inflammatory responsesRequirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cellsVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteLeukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytesThe adaptor 3BP2 is required for KIT receptor expression and human mast cell survivalCherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages.Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in miceBone marrow transplantation improves autoinflammation and inflammatory bone loss in SH3BP2 knock-in cherubism miceEtanercept administration to neonatal SH3BP2 knock-in cherubism mice prevents TNF-α-induced inflammation and bone loss.SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.The adaptor 3BP2 is required for early and late events in FcεRI signaling in human mast cells.Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells.Enhancement of B-cell receptor signaling by a point mutation of adaptor protein 3BP2 identified in human inherited disease cherubism.3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functionsA concerted HIF-1α/MT1-MMP signalling axis regulates the expression of the 3BP2 adaptor protein in hypoxic mesenchymal stromal cells3BP2 adapter protein is required for receptor activator of NFκB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells.Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFATAdaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase.The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function.TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.Adapter molecules in T cell receptor signaling.SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis modelThe transmembrane adapter LAT plays a central role in immune receptor signalling.Beyond the RING: CBL proteins as multivalent adapters.Adapters in the organization of mast cell signaling.Cherubism gene Sh3bp2 is important for optimal bone formation, osteoblast differentiation, and function.RNA therapeutics targeting osteoclast-mediated excessive bone resorption.The role of SH3BP2 in the pathophysiology of cherubism.T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice.3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation.SH3BP2 is an activator of NFAT activity and osteoclastogenesis.The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response.Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.Syk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells.SH3BP2 mutations potentiate osteoclastogenesis via PLCγ.
P2860
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P2860
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@ast
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@en
type
label
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@ast
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@en
prefLabel
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@ast
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@en
P2093
P1433
P1476
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
@en
P2093
J Hernandez
S Tartare-Deckert
P304
P356
10.1016/S1074-7613(00)80657-3
P407
P577
1998-11-01T00:00:00Z