Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins.
about
Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinaseUse of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisIdentification and functional characterization of an Src homology domain 3 domain-binding site on CblA novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytesGrit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter moleculesPhosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicityAnalysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptorsA tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulationProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesWeak binding to E3 ubiquitin ligase c-Cbl increases EGFRvA protein stabilitycbl-b inhibits epidermal growth factor receptor signalingThe involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activationEvidence for direct interaction between Sprouty and CblThe adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interactionThe protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 cateninRegulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptorDifferential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1)Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cellsThe CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cellsThe Cbl interactome and its functionsA novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cellsCbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinaseFyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cellsShc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytesThe N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases.Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pitsTyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation.CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins.T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.Epidermal Growth Factor Receptor Cell Proliferation Signaling PathwaysRoles of E3 ubiquitin ligases in cell adhesion and migration.Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells.Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex.
P2860
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P2860
Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@ast
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@en
type
label
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@ast
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@en
prefLabel
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@ast
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@en
P2093
P2860
P356
P1476
Tyrosine phosphorylation of Cb ...... downstream signaling proteins.
@en
P2093
P2860
P304
14554-14559
P356
10.1074/JBC.271.24.14554
P407
P577
1996-06-01T00:00:00Z