PI3K integrates the action of insulin and leptin on hypothalamic neurons. - Wikidata - wikimedia - TriplyDB

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

http://www.wikidata.org/entity/Q30475788

about

PI3K: An Attractive Candidate for the Central Integration of Metabolism and Reproduction An inducible CiliaGFP mouse model for in vivo visualization and analysis of cilia in live tissue.Recent advances in understanding leptin signaling and leptin resistance Effects of hypothalamic neurodegeneration on energy balance.Pancreatic regulation of glucose homeostasis Leptin signaling and leptin resistance Central nervous control of energy and glucose balance: focus on the central melanocortin system Acute leptin treatment enhances functional recovery after spinal cord injury Nutritional programming in the rat is linked to long-lasting changes in nutrient sensing and energy homeostasis in the hypothalamus Possible Integrative Actions of Leptin and Insulin Signaling in the Hypothalamus Targeting Energy Homeostasis Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene Leptin monotherapy rescues spermatogenesis in male Akita type 1 diabetic mice Hormone and glucose signalling in POMC and AgRP neurons.The role of insulin receptor substrate 2 in hypothalamic and beta cell function.A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells.AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels.Hypothalamic pathways linking energy balance and reproduction.Central leptin receptor action and resistance in obesity.Functional consequences of the human leptin receptor (LEPR) Q223R transversion.Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis.Functional role of c-Jun-N-terminal kinase in feeding regulation.Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130.Leptin receptor modulation of adiposity and fertility Leptin Induces Mitosis and Activates the Canonical Wnt/β-Catenin Signaling Pathway in Neurogenic Regions of Xenopus Tadpole Brain.Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice.PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors.Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo.Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system.Erk1/2 mediates leptin receptor signaling in the ventral tegmental area.Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats.

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P2860

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

http://www.wikidata.org/entity/Q30475788

description

2005 nî lūn-bûn

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2005 թուականի Մարտին հրատարակուած գիտական յօդուած

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2005 թվականի մարտին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

@zh-hk

2005年論文

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2005年論文

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2005年论文

@wuu

name

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

@ast

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

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type

label

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

@ast

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

@en

prefLabel

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

@ast

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

@en

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P1433

Journal of Clinical Investigation

P1476

PI3K integrates the action of insulin and leptin on hypothalamic neurons.

@en

P2093

Allison Wanting Xu

http://www.w3.org/2001/XMLSchema#string

Christopher B Kaelin

http://www.w3.org/2001/XMLSchema#string

Gregory S Barsh

http://www.w3.org/2001/XMLSchema#string

Kiyoshi Takeda

http://www.w3.org/2001/XMLSchema#string

Michael W Schwartz

http://www.w3.org/2001/XMLSchema#string

P2860

A simplified system for generating recombinant adenoviruses

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

The phosphoinositide 3-kinase pathway

Generalized lacZ expression with the ROSA26 Cre reporter strain

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats

Intracellular signalling. Key enzyme in leptin-induced anorexia

A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding

Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

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951-958

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10.1172/JCI24301

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7971951

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15761497

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1062894

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