Structure and function of cellular deoxyribonucleoside kinases.
about
Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1Structures of thymidine kinase 1 of human and mycoplasmic originThe sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analoguesStructural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analoguesEnzymology of purine and pyrimidine antimetabolites used in the treatment of cancerNonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosidesStructural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinaseKinetic properties of mutant deoxyguanosine kinase in a case of reversible hepatic mtDNA depletionN3-substituted thymidine bioconjugates for cancer therapy and imagingStructural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate bindingFunctional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase. Investigations of the putative catalytic glutamate-arginine pair and of residues responsible for substrate specificityStructural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinasePhosphodeoxyribosyltransferases, Designed Enzymes for Deoxyribonucleotides SynthesisPan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide MetabolismCell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma bruceiStructure of a type II thymidine kinase with bound dTTPReaction of human UMP-CMP kinase with natural and analog substratesLong-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cellsAlgorithmic modeling quantifies the complementary contribution of metabolic inhibitions to gemcitabine efficacyStructural and Kinetic Characterization of Thymidine Kinase from Leishmania majorThymidine kinase 1 regulatory fine-tuning through tetramer formationNon-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities.Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificitySingle amino acid chelates (SAAC): a strategy for the design of technetium and rhenium radiopharmaceuticals.Transcriptome analysis reveals potential mechanisms underlying differential heart development in fast- and slow-growing broilers under heat stress.Engineering Kinases to Phosphorylate Nucleoside Analogs for Antiviral and Cancer Therapy.XPA-210: a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma.Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil.(18)F-FLT PET/CT imaging in a Wister rabbit inflammation model.Requirement for deoxycytidine kinase in T and B lymphocyte development.Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme.SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity.2-(1,3-Dioxoisoindolin-2-yl)ethyl 4-methyl-benzene-sulfonate.Characterization of oligomeric and kinetic properties of tomato thymidine kinase 1.1-(Phthalimidometh-yl)pyridinium p-toluene-sulfonate.2-({3-[(2R,4S,5R)-4-Hydr-oxy-5-hydroxy-methyl-2,3,4,5-tetra-hydro-furan-2-yl]-5-methyl-2,6-dioxo-1,2,3,6-tetra-hydro-pyrimidin-1-yl}meth-yl)isoindoline-1,3-dione.Quaternary structures of recombinant, cellular, and serum forms of thymidine kinase 1 from dogs and humans.Borononucleotides as substrates/binders for human NMP kinases: enzymatic and spectroscopic evaluation.
P2860
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P2860
Structure and function of cellular deoxyribonucleoside kinases.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structure and function of cellular deoxyribonucleoside kinases.
@ast
Structure and function of cellular deoxyribonucleoside kinases.
@en
type
label
Structure and function of cellular deoxyribonucleoside kinases.
@ast
Structure and function of cellular deoxyribonucleoside kinases.
@en
prefLabel
Structure and function of cellular deoxyribonucleoside kinases.
@ast
Structure and function of cellular deoxyribonucleoside kinases.
@en
P2093
P1476
Structure and function of cellular deoxyribonucleoside kinases.
@en
P2093
Eriksson S
Johansson K
Munch-Petersen B
P2888
P304
P356
10.1007/S00018-002-8511-X
P577
2002-08-01T00:00:00Z
P6179
1023165600