Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn.
about
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytesOccurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytesPodocytesLinking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusRoles of adaptor proteins in podocyte biologyFyn binds to and phosphorylates the kidney slit diaphragm component NephrinSIRPĪ± interacts with nephrin at the podocyte slit diaphragmNephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signalingSignificance analysis of time course microarray experiments.Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins.The pathogenesis, diagnosis and treatment of lupus nephritis.Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease.Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient micec-mip impairs podocyte proximal signaling and induces heavy proteinuriaC-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.Basophils and the T helper 2 environment can promote the development of lupus nephritis.Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets.Susceptibility genes in the pathogenesis of murine lupus.Increased SHP-1 protein expression by high glucose levels reduces nephrin phosphorylation in podocytesGlomerular proteinuria: a complex interplay between unique players.Biomarkers for kidney involvement in pediatric lupus.The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase LynSrc protein tyrosine kinase family and acute inflammatory responses.Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxisMultiple roles of Lyn kinase in myeloid cell signaling and function.Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses.Basophils, IgE, and autoantibody-mediated kidney diseaseTyrosine kinase signaling in kidney glomerular podocytes.Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis.Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes.Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1).Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus.Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin.Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.Autoantibodies in SLE: Specificities, Isotypes and ReceptorsRecent Progress in the Pathogenesis of Nephrotic Proteinuria
P2860
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P2860
Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn.
description
2001 nĆ® lÅ«n-bĆ»n
@nan
2001 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
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Õ¤ÕøÖÕ”Õ®
@hyw
2001 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¶Õ¾Õ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2001幓ć®č«ę
@ja
2001幓č«ę
@yue
2001幓č«ę
@zh-hant
2001幓č«ę
@zh-hk
2001幓č«ę
@zh-mo
2001幓č«ę
@zh-tw
2001幓č®ŗę
@wuu
name
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@ast
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@en
type
label
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@ast
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@en
prefLabel
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@ast
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@en
P2093
P1433
P1476
Lupus-like kidney disease in m ...... tyrosine kinases Lyn and Fyn.
@en
P2093
P356
10.1016/S0960-9822(00)00024-5
P407
P577
2001-01-01T00:00:00Z