Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A. - Wikidata - wikimedia - TriplyDB

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

http://www.wikidata.org/entity/Q33245438

about

The biology of DHX9 and its potential as a therapeutic target The RNA helicase A in malignant transformation Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes Potential approaches to the treatment of Ewing's sarcoma YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro.High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition New strategies in ewing sarcoma: lost in translation?Ewing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions.Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing.Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors.Ewing sarcoma EWS protein regulates midzone formation by recruiting Aurora B kinase to the midzone Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.RNA helicases: emerging roles in viral replication and the host innate response.Novel, Broad Spectrum Anti-Cancer Agents Containing the Tricyclic 5:7:5-Fused Diimidazodiazepine Ring System.RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1.Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.3D tissue-engineered model of Ewing's sarcoma Synthesis and structure-activity relationship studies of small molecule disruptors of EWS-FLI1 interactions in Ewing's sarcoma.Ewing sarcoma ewsa protein regulates chondrogenesis of Meckel's cartilage through modulation of Sox9 in zebrafish.Targeted therapies for advanced Ewing sarcoma family of tumors.Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level.RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.Recent advances in the molecular pathogenesis of Ewing's sarcoma.Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets.Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma.Superfamily 2 helicases Molecular abnormalities in Ewing's sarcoma.A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma.Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in Ewing Sarcoma.Ewing sarcoma: biology-based therapeutic perspectives.Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities.The clinical development of p53-reactivating drugs in sarcomas - charting future therapeutic approaches and understanding the clinical molecular toxicology of Nutlins.Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9.In vitro and in vivo analysis of the interaction between RNA helicase A and HIV-1 RNA.

P2860

Q26749166-A91DBA2C-1232-49CA-9748-3843224A6A78 Q26765181-EA69E9B9-A73B-4FFA-9F72-8922DF891EF2 Q26801785-A3D3297E-4124-4DDF-ADBF-5A280C289EC5 Q28072744-426E984A-C449-4B6F-914D-051055A7D2A3 Q28477993-522BC386-EF76-4E75-AB4D-5BAB4A8C6977 Q30427325-D7A7E2E2-1179-4C47-87F2-8F45453121BE Q31106858-37C62008-F0FF-430F-9F41-200D3A7623C0 Q33750221-DF3F3DCB-ABB2-43C5-BF62-C2648C37A4F7 Q33758471-00988980-9A23-4310-8DE9-251A614F20B4 Q33861072-D75DE7F7-7693-400D-AC09-B8F8BED014A9 Q33983533-2CDFD39E-5356-482E-B853-2924A337698F Q34011147-FFC6B42D-BA96-4ECB-8081-CB6E3A0C05C7 Q34021681-6BBB5587-17E9-4E4D-A525-E40C77D7D927 Q34028538-B47732D4-927D-4CF0-A75A-CBEF5CE74DA1 Q34155816-F3C60193-519F-4ECB-9719-960A86051E75 Q34155934-E66D6072-7A6E-40A2-A906-88826666899D Q34975091-E8485617-2ABC-4B9D-8B01-E80372F8109D Q35097968-0115C796-A155-45C4-B7EA-7580EDA0E424 Q35212670-5713587D-2D19-4FDE-8D80-2A6F6F545F1F Q35428655-56150EDC-674D-449E-A51C-CA556ABCA74A Q35458552-84F74A3C-3A84-4D4A-B24B-081284F15170 Q35548582-50E6A0ED-8D24-4C95-B9C8-F6704D9D88F9 Q35589492-C47A8CB4-F47A-4BB6-9D75-0E73F9508381 Q35723398-C3F26C04-44F6-4317-B128-3CB01C11ADA3 Q35963798-575CA182-7E8B-43D0-BA71-E038F5F503D9 Q36287019-3964EF8D-59D7-42FF-B179-6D2F5EBB4EEC Q36545848-6D01FA40-79DE-4872-8C7D-6F75839D3B10 Q36562720-86C67F66-A97D-4937-B86D-492032D49B2B Q36562726-9D81AE11-18E5-4559-BAC4-F21C7566051D Q36930039-57432CC6-AB03-4B9A-B065-5AAF3E20A33C Q37178493-3D541FFD-D281-4816-A726-A6B4236BACD8 Q37300040-0729114A-E116-4419-B36A-D4D3CB2C582D Q37421771-9DF8FF4A-9896-4941-AD39-279A29327404 Q37660292-687ECAD8-5840-4D83-A24D-219462CA9287 Q37981253-20ACFBDB-C373-4EE4-8749-D644C4DCA3CD Q38006606-E3757D47-1D91-409C-9946-FBC12B5E4A9D Q38192005-265C7FD0-CEA4-48C5-B2F5-2EC874FD81B0 Q38243878-935C2C78-57D7-4B79-8F34-B722A7F1DE02 Q38260741-F75BEBC9-3B5C-4BCE-A860-92095FF0818F Q38321340-0C30CE73-9BC1-4866-99BB-29A254ECBA08

P2860

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

http://www.wikidata.org/entity/Q33245438

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@ast

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@en

type

label

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@ast

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@en

prefLabel

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@ast

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@en

P1433

Q33245438-C7B5D762-E3A7-418C-B4A9-56C37A6391A3

P1476

Q33245438-E6E04DC4-07BD-4690-A0D4-2BE1D7F45E20

P2093

Q33245438-1FFE231E-C38E-416E-B056-4C64B3998047

Q33245438-277D9D6D-4FAC-4216-AD8A-7DF13C806F80

Q33245438-56DA4B80-9D3E-4B05-B9C3-014121B079D7

Q33245438-8713BF0D-8970-4D4A-AFD4-24E3AFB3E744

Q33245438-958606AA-B112-4AAE-9E93-97C48B7971B9

Q33245438-BDFD60AB-180C-4259-81D2-D0CA9527FC8C

Q33245438-BE89E964-07C3-46CE-A452-23E5272054A7

Q33245438-C59945A4-77D5-4D6C-A008-4E0405511CA7

Q33245438-D316EA7F-7F93-47E2-8B2F-754C13347B09

P304

Q33245438-C3BD3072-D4D6-4FEC-A81E-3EA2440825D1

P31

Q33245438-E96A8B11-DE42-4615-93F4-1B9C7D03A97F

P356

Q33245438-835C1128-9375-40FC-8220-07CF01A35B97

P407

Q33245438-4BAC17AD-F188-41C1-ADFA-6C2AEE309015

P433

Q33245438-0B611DF7-739A-42CB-BC42-76CDCEFD067A

P478

Q33245438-6966201F-97BE-404F-B83E-A21F27868815

P577

Q33245438-0193D11C-4AE3-49A0-8275-1FF7138D2732

P698

Q33245438-9F0F4393-3EC2-4466-A400-8C1240297387

P356

0008-5472.CAN-05-3293

P1433

Cancer Research

P1476

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

@en

P2093

Amy Levenson

http://www.w3.org/2001/XMLSchema#string

Anna M Rice

http://www.w3.org/2001/XMLSchema#string

Aykut Uren

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Toretsky

http://www.w3.org/2001/XMLSchema#string

Jeffrey D Parvin

http://www.w3.org/2001/XMLSchema#string

Ogan D Abaan

http://www.w3.org/2001/XMLSchema#string

Sean Bong Lee

http://www.w3.org/2001/XMLSchema#string

Timothy P Cripe

http://www.w3.org/2001/XMLSchema#string

Verda Erkizan

http://www.w3.org/2001/XMLSchema#string

P304

5574-5581

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-05-3293

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

66

http://www.w3.org/2001/XMLSchema#string

P577

2006-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16740692

http://www.w3.org/2001/XMLSchema#string