An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS
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Global phenotypic screening for antimalarialsOpen Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos ArylpyrrolesRecent advances in malaria drug discoveryPlasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial HitAntimalarial drug discovery - approaches and progress towards new medicines.A new in vivo screening paradigm to accelerate antimalarial drug discoveryIdentification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaignA New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug DiscoveryTaking Open Innovation to the Molecular Level - Strengths and LimitationsCyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS).A Divergent SAR Study Allows Optimization of a Potent 5-HT2c Inhibitor to a Promising Antimalarial Scaffold.Evaluation of aminohydantoins as a novel class of antimalarial agents.Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screenMiniaturized Cultivation of Microbiota for Antimalarial Drug Discovery.Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum.Antiplasmodial dihetarylthioethers target the coenzyme A synthesis pathway in Plasmodium falciparum erythrocytic stagesSynthesis and Pharmacological Evaluation of 4-Iminothiazolidinones for Inhibition of PI3 KinaseSelection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi.A Quinoline Carboxamide Antimalarial Drug Candidate Uniquely Targets Plasmodia at Three Stages of the Parasite Life Cycle.Case Study of Small Molecules As Antimalarials: 2-Amino-1-phenylethanol (APE) Derivatives.Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library.
P2860
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P2860
An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@ast
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@en
type
label
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@ast
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@en
prefLabel
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@ast
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@en
P2093
P2860
P356
P1476
An Invitation to Open Innovati ...... Starting Points from the TCAMS
@en
P2093
David Barros
Esther Fernández
Esther Porras
Francisco Javier Gamo
Félix Calderón
José Luís Lavandera
José María Bueno
José María Fiandor
José Miguel Coterón
Julia Castro
P2860
P304
P356
10.1021/ML200135P
P577
2011-08-03T00:00:00Z