Control of lymphocyte development by the Ikaros gene family.
about
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexesSoluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulationIkaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activityUnconventional potentiation of gene expression by IkarosVasoactive intestinal peptide receptor-1 (VPAC-1) is a novel gene target of the hemolymphopoietic transcription factor IkarosLenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cellsDown-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activatorMultiple hematopoietic defects and delayed globin switching in Ikaros null miceIkaros integrates endocrine and immune system developmentAn essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary-mediated somatic growth.Ikaros SUMOylation: switching out of repressionMutations of the Drosophila zinc finger-encoding gene vielfältig impair mitotic cell divisions and cause improper chromosome segregation.Identification of two Ikaros-like transcription factors in lamprey.Isolation and characterization of lymphocyte-like cells from a lamprey.Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene.Ikaros, a lymphoid-cell-specific transcription factor, contributes to the leukemogenic phenotype of a mink cell focus-inducing murine leukemia virusEpigenetic regulation of T cell fate and function.Peripheral natural killer cell maturation depends on the transcription factor AiolosThe combined expression patterns of Ikaros isoforms characterize different hematological tumor subtypesNotch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-mycTargeting of Ikaros to pericentromeric heterochromatin by direct DNA bindingGenetic control of NKT cell numbers.Allelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood.At the crossroads: diverse roles of early thymocyte transcriptional regulators.Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells.Ikaros represses the transcriptional response to Notch signaling in T-cell development.Ikaros expression sensitizes leukemic cells to the chemotherapeutic drug doxorubicinIkaros sets the potential for Th17 lineage gene expression through effects on chromatin state in early T cell development.A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development.A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis.Casein Kinase II (CK2), Glycogen Synthase Kinase-3 (GSK-3) and Ikaros mediated regulation of leukemia.IKAROS expression in distinct bone marrow cell populations as a candidate biomarker for outcome with lenalidomide-dexamethasone therapy in multiple myeloma.TP53 Mutations in Hypodiploid Acute Lymphoblastic Leukemia.The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma.Control of IL-2Ralpha gene expression: structural changes within the proximal enhancer/core promoter during T-cell development.MLL-ENL cooperates with SCF to transform primary avian multipotent cells.Ikaros, Helios, and Aiolos protein levels increase in human thymocytes after β selection.A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition
P2860
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P2860
Control of lymphocyte development by the Ikaros gene family.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Control of lymphocyte development by the Ikaros gene family.
@ast
Control of lymphocyte development by the Ikaros gene family.
@en
type
label
Control of lymphocyte development by the Ikaros gene family.
@ast
Control of lymphocyte development by the Ikaros gene family.
@en
prefLabel
Control of lymphocyte development by the Ikaros gene family.
@ast
Control of lymphocyte development by the Ikaros gene family.
@en
P2093
P1476
Control of lymphocyte development by the Ikaros gene family.
@en
P2093
P304
P356
10.1016/S0952-7915(99)80028-4
P577
1999-04-01T00:00:00Z