Proteasome inhibitors block development of Plasmodium spp.
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Why bortezomib cannot go with 'green'?Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivityThiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplastEvidence for catalytic roles for Plasmodium falciparum aminopeptidase P in the food vacuole and cytosolMarine actinomycetes: a new source of compounds against the human malaria parasiteApplication of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VIBlocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primatesTargeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistancePlasmodium falciparum origin recognition complex subunit 5: functional characterization and role in DNA replication foci formationA Novel and Conserved Plasmodium Sporozoite Membrane Protein SPELD is Required for Maturation of Exo-erythrocytic FormsHIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites.Data-mining approaches reveal hidden families of proteases in the genome of malaria parasiteAntimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL3BDeciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence.Lys48 ubiquitination during the intraerythrocytic cycle of the rodent malaria parasite, Plasmodium chabaudiHIV treatments reduce malaria liver stage burden in a non-human primate model of malaria infection at clinically relevant concentrations in vivoThe Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite.Analysis of proteasomal proteolysis during the in vitro metacyclogenesis of Trypanosoma cruziThe Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands.Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probesMetamorphosis of the malaria parasite in the liver is associated with organelle clearanceInhibition of Plasmodium sporozoites infection by targeting the host cell.Activity of a trisubstituted pyrrole in inhibiting sporozoite invasion and blocking malaria infection.Protease-associated cellular networks in malaria parasite Plasmodium falciparum.Roles of the amino terminal region and repeat region of the Plasmodium berghei circumsporozoite protein in parasite infectivityIdentification of potent and selective non-covalent inhibitors of the Plasmodium falciparum proteasome.Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicityThe malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host.Exploiting unique structural and functional properties of malarial glycolytic enzymes for antimalarial drug developmentPotent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen.Effects of cyclin-dependent kinase inhibitor Purvalanol B application on protein expression and developmental progression in intra-erythrocytic Plasmodium falciparum parasites.Characterisation of 20S Proteasome in Tritrichomonas foetus and Its Role during the Cell Cycle and Transformation into Endoflagellar Form.Plasmodium sporozoites trickle out of the injection siteThe alveolin IMC1h is required for normal ookinete and sporozoite motility behaviour and host colonisation in Plasmodium berghei.HIV nonnucleoside reverse transcriptase inhibitors and trimethoprim-sulfamethoxazole inhibit plasmodium liver stages.Transformation of sporozoites into early exoerythrocytic malaria parasites does not require host cellsHigh-resolution cryo-EM proteasome structures in drug development.A rapid and scalable density gradient purification method for Plasmodium sporozoitesStructure- and function-based design of Plasmodium-selective proteasome inhibitors
P2860
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P2860
Proteasome inhibitors block development of Plasmodium spp.
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Proteasome inhibitors block development of Plasmodium spp.
@ast
Proteasome inhibitors block development of Plasmodium spp.
@en
type
label
Proteasome inhibitors block development of Plasmodium spp.
@ast
Proteasome inhibitors block development of Plasmodium spp.
@en
prefLabel
Proteasome inhibitors block development of Plasmodium spp.
@ast
Proteasome inhibitors block development of Plasmodium spp.
@en
P2093
P2860
P356
P1476
Proteasome inhibitors block development of Plasmodium spp
@en
P2093
M R Briones
V Nussenzweig
P2860
P304
P356
10.1128/AAC.42.10.2731
P407
P577
1998-10-01T00:00:00Z