Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins.
about
Sorting of ligand-activated epidermal growth factor receptor to lysosomes requires its actin-binding domainRegulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes.Clathrin-dependent endocytosisMig-6 is a negative regulator of the epidermal growth factor receptor signalClathrin-mediated endocytosis in AP-2-depleted cellsRequirement for the adapter protein GRB2 in EGF receptor endocytosis.Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis.Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases.Recognition of sorting signals by clathrin adaptors.Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticlesTargeting the EGFR signaling pathway in cancer therapy.Clathrin function in yeast endocytosis.Checkpoints for vesicular traffic?Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epitheliumIn vitro binding of clathrin adaptors to sorting signals correlates with endocytosis and basolateral sorting.Endocytosis of activated receptors and clathrin-coated pit formation: deciphering the chicken or egg relationship.Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable componentsThe LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformationTyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.Distinct endocytic responses of heteromeric and homomeric transforming growth factor beta receptorsEndocytic downregulation of ErbB receptors: mechanisms and relevance in cancerThe Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface.Phosphorylation-dependent trafficking of plasma membrane proteins in animal and plant cells.Distinct saturable pathways for the endocytosis of different tyrosine motifs.The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling.Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif.Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization.Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tail.Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera.Novel mechanism for regulation of epidermal growth factor receptor endocytosis revealed by protein kinase A inhibition.Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain.Regulated migration of epidermal growth factor receptor from caveolae.A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes.Partitioning of proteins into plasma membrane microdomains. Clustering of mutant influenza virus hemagglutinins into coated pits depends on the strength of the internalization signal.Mutational analysis of the nucleotide binding site of the epidermal growth factor receptor and v-Src protein-tyrosine kinases.Regulatory mechanisms that modulate signalling by G-protein-coupled receptors.A ligand-inducible anaplastic lymphoma kinase chimera is endocytosis impaired.Ligand-induced clathrin-mediated endocytosis of the keratinocyte growth factor receptor occurs independently of either phosphorylation or recruitment of eps15.Mu 2 binding directs the cystic fibrosis transmembrane conductance regulator to the clathrin-mediated endocytic pathway.
P2860
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P2860
Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins.
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@ast
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@en
type
label
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@ast
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@en
prefLabel
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@ast
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@en
P2093
P2860
P356
P1476
Ligand-induced endocytosis of ...... e in binding adaptor proteins.
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.19.8719
P407
P577
1995-09-01T00:00:00Z