The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface.
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The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent mannerPTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling.Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signalingRegulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factorsTurning off AKT: PHLPP as a drug targetPTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastomaReceptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1Functions of the cytoplasmic tails of the human receptor activity-modifying protein components of calcitonin gene-related peptide and adrenomedullin receptorsThe Role of PTEN in Tumor AngiogenesisVinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface.Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cellsNHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymomaProlonged exposure of colon cancer cells to the epidermal growth factor receptor inhibitor gefitinib (Iressa(TM)) and to the antiangiogenic agent ZD6474: Cytotoxic and biomolecular effects.NHERF1/EBP50 in Breast Cancer: Clinical PerspectivesPeritumoral vascular invasion and NHERF1 expression define an immunophenotype of grade 2 invasive breast cancer associated with poor prognosis.NHERF1/EBP50 is a new marker in colorectal cancer.EGF-induced expansion of migratory cells in the rostral migratory stream.NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1).Phosphorylation of EBP50 negatively regulates β-PIX-dependent Rac1 activity in anoikis.Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin-binding phosphoprotein 50 in cholangiocarcinoma.Contact-dependent inhibition of EGFR signaling by Nf2/MerlinEBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation.EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration.Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencingNa/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.Nf2/Merlin: a coordinator of receptor signalling and intercellular contactEstablishment of HIV-1 model cell line GHOST(3) with stable DRiP78 and NHERF1 knockdown.Endocytosis of receptor tyrosine kinasesSignificant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancerEzrin-radixin-moesin-binding phosphoprotein (EBP50), an estrogen-inducible scaffold protein, contributes to biliary epithelial cell proliferationThe cellular distribution of Na+/H+ exchanger regulatory factor 1 is determined by the PDZ-I domain and regulates the malignant progression of breast cancer.Nuclear NHERF1 expression as a prognostic marker in breast cancer.Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer Cells.NHERF1 regulates the progression of colorectal cancer through the interplay with VEGFR2 pathwayInactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer.Role of the PDZ-scaffold protein NHERF1/EBP50 in cancer biology: from signaling regulation to clinical relevance.
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The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 October 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
@en
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
@nl
type
label
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
@en
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
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prefLabel
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
@en
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
@nl
P2093
P2860
P356
P1476
The Na+/H+ exchanger regulator ...... receptors at the cell surface.
@en
P2093
Catherine M Cresson
Cheri S Lazar
Gordon N Gill
P2860
P304
P356
10.1091/MBC.E04-03-0239
P577
2004-10-06T00:00:00Z