A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes.
about
Differential roles of syntaxin 7 and syntaxin 8 in endosomal traffickingHuman VPS34 is required for internal vesicle formation within multivesicular endosomesThe Juxtamembrane Region of the EGF Receptor Functions as an Activation DomainThe vesicular acetylcholine transporter interacts with clathrin-associated adaptor complexes AP-1 and AP-2Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein.Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes.Regulation of receptor tyrosine kinase signaling by endocytic trafficking.Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases.Transforming growth factor beta receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor.Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways.HER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanismsE3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes.β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells.A tyrosine-based signal plays a critical role in the targeting and function of adenovirus RIDalpha proteinAdenovirus RIDalpha regulates endosome maturation by mimicking GTP-Rab7.Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activationEpithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway.Molecular kinetics of nerve growth factor receptor trafficking and activationRegulation of epidermal growth factor receptor degradation by heterotrimeric Galphas proteinThe regulatory role of the juxtamembrane region in the activity of the epidermal growth factor receptor.Novel mechanism for regulation of epidermal growth factor receptor endocytosis revealed by protein kinase A inhibition.Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core.EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain.Regulation of EGF signaling by cell polarity in MDCK kidney epithelial cells.Mutual cross-talk between fibronectin integrins and the EGF receptor: Molecular basis and biological significance.Gab1 signaling is regulated by EGF receptor sorting in early endosomes.Focus on "EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain".Role of two dileucine-like motifs in insulin receptor anchoring to microvilli.Identification of multivesicular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells.A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor.Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in MDCK cells.GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.
P2860
Q22010801-56035765-3104-42CC-BD66-ACF0434E859FQ24652429-9E0B6026-B1CE-4148-9961-170030E47DA2Q27646344-41D415E9-0206-4BF5-BADC-38EB7603A8C4Q28571417-76C87578-8E35-4178-8699-FA26935EDABAQ30412396-B4A4BB8F-7427-47D7-85A7-B8319FFD3988Q31048369-07F42708-7AF9-47A7-A626-BB55F0C4DDADQ32029952-85F2B921-2A11-41DF-BF09-67DF729DFE88Q32062433-E5BAAF09-10A3-493E-B0EF-C070E0C172C3Q33946788-073ED6D9-39BB-4724-BDC6-2576C0196AE6Q34029358-D8234B45-A78B-4034-9D31-436AD2972207Q34183239-04FE89E9-CED4-45A5-9F53-8A6B51B446AAQ34768713-793F2513-44B6-4C99-A9F9-1ED65CE2366AQ35551725-9DBE3163-8DF4-41D3-AB58-DE85F2145EDEQ36099116-68956859-73CA-4F0C-9F97-ABBF08D7E2A0Q36176585-364BAB9E-9328-4294-A5D9-0096BECE3A12Q36288511-4B9F0993-B496-4448-A479-EE3E1F35ECB7Q36947703-4910B126-9683-40E6-8EE4-F1DC8A95D828Q37218752-B1407419-24AB-4802-A234-8D72F81FF32CQ37657338-751E7DCF-FB0E-404F-8523-437AEAC233CCQ37977179-9A6F48FB-7549-49BE-A2C2-2783FC6250EEQ39586494-FF3D6425-70B5-44CA-A53C-B95F2A697329Q40646939-991335CF-B78B-43A3-831D-82E94346414BQ40713310-D16289B5-10EE-46E9-9069-9B3642178606Q40752386-066267E2-9304-467F-9900-5A745348F6F4Q40927098-32618EC4-4ED7-4CE9-9C2E-C071AE75815BQ42174975-628F29D2-B2AF-42C8-82FF-0453BF8CC45EQ42801574-1DDDB412-0737-40F0-8B41-E775323BDB81Q43879131-CBBC809B-31A3-4635-BB9B-1B34156A735EQ44129445-150B532E-AF45-4CD7-AB91-42BF0ED2EFD1Q44770049-30D5AE91-D9B1-4030-A654-40FF625C9F16Q46445840-A59C84E8-4822-47D3-A70B-8AF8186C6C0DQ47234461-06DBD7B0-CA3D-4007-8E38-42FA32E787F6Q49530976-36F08752-43D6-4DF5-9DA0-F89917292455
P2860
A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A leucine-based determinant in ...... ceptor complexes to lysosomes.
@en
type
label
A leucine-based determinant in ...... ceptor complexes to lysosomes.
@en
prefLabel
A leucine-based determinant in ...... ceptor complexes to lysosomes.
@en
P2093
P2860
P356
P1476
A leucine-based determinant in ...... ceptor complexes to lysosomes.
@en
P2093
P2860
P304
P356
10.1074/JBC.274.5.3141
P407
P577
1999-01-01T00:00:00Z