Disruption of the talin gene arrests mouse development at the gastrulation stage. - Wikidata - wikimedia - TriplyDB

Disruption of the talin gene arrests mouse development at the gastrulation stage.

Disruption of the talin gene arrests mouse development at the gastrulation stage.

http://www.wikidata.org/entity/Q33925712

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle The integrin-actin connection, an eternal love affair The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration Integrin-based therapeutics: biological basis, clinical use and new drugs Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain The Structure of an Interdomain Complex That Regulates Talin Activity Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin Extracellular rigidity sensing by talin isoform-specific mechanical linkages MEK kinase activity is not necessary for Raf-1 function.Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.Integrins and integrin-associated proteins in the cardiac myocyte.Induction of focal adhesions and motility in Drosophila S2 cells Localization of an integrin binding site to the C terminus of talin.Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation Evidence that talin alternative splice variants from Ciona intestinalis have different roles in cell adhesion Structural and mechanical functions of integrins.Talins and kindlins: partners in integrin-mediated adhesion.Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain.Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.Talin B is required for force transmission in morphogenesis of Dictyostelium.Talin-dependent integrin activation is required for fibrin clot retraction by platelets.Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle Regulator of G-Protein Signalling-14 (RGS14) Regulates the Activation of αMβ2 Integrin during Phagocytosis.Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms Vinculin and talin: focus on the myocardium Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor Blocking neutrophil integrin activation prevents ischemia-reperfusion injury Talin determines the nanoscale architecture of focal adhesions.Cooperative Stimulation of Megakaryocytic Differentiation by Gfi1b Gene Targets Kindlin3 and Talin1 Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish Overlapping functions of the two talin homologues in Dictyostelium Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3

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P2860

Disruption of the talin gene arrests mouse development at the gastrulation stage.

http://www.wikidata.org/entity/Q33925712

description

2000 nî lūn-bûn

@nan

2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Disruption of the talin gene arrests mouse development at the gastrulation stage.

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Disruption of the talin gene arrests mouse development at the gastrulation stage.

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type

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Disruption of the talin gene arrests mouse development at the gastrulation stage.

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Disruption of the talin gene arrests mouse development at the gastrulation stage.

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prefLabel

Disruption of the talin gene arrests mouse development at the gastrulation stage.

@ast

Disruption of the talin gene arrests mouse development at the gastrulation stage.

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Developmental Dynamics

P1476

Disruption of the talin gene arrests mouse development at the gastrulation stage.

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P2093

Brown JE

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Critchley DR

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Fässler R

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Giblett SM

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Hemmings L

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Zhou XH

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P2860

Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles

Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro

Functional and biochemical analysis of the C2 domains of synaptotagmin IV

Perlecan maintains the integrity of cartilage and some basement membranes

A new protein of adhesion plaques and ruffling membranes

Three-dimensional segregation of supramolecular activation clusters in T cells

Sequence and domain structure of talin

Consequences of lack of beta 1 integrin gene expression in mice

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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