The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. - Wikidata - wikimedia - TriplyDB

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.

http://www.wikidata.org/entity/Q34151349

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Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides A Mouse Model of Zika Virus Pathogenesis Cyclic di-GMP sensing via the innate immune signaling protein STING Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.STING is a direct innate immune sensor of cyclic di-GMP Cytosolic Innate Immune Sensing and Signaling upon Infection STING: infection, inflammation and cancer Sensors of Infection: Viral Nucleic Acid PRRs in Fish Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections Cyclic di-GMP: the first 25 years of a universal bacterial second messenger Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants Innate immune responses to DNA viruses Species-specific detection of the antiviral small-molecule compound CMA by STING Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding Innate immune detection of microbial nucleic acids.Molecular Pathways: Targeting the Stimulator of Interferon Genes (STING) in the Immunotherapy of Cancer International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease Cytoplasmic DNA innate immune pathways Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response Cyclic di-GMP-dependent signaling pathways in the pathogenic Firmicute Listeria monocytogenes Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection The transcription factor IRF3 triggers "defensive suicide" necrosis in response to viral and bacterial pathogens NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING Mycobacterium tuberculosis Rv3586 (DacA) is a diadenylate cyclase that converts ATP or ADP into c-di-AMP.The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons A Redox-Responsive Transcription Factor Is Critical for Pathogenesis and Aerobic Growth of Listeria monocytogenes.Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.cGAS is essential for cellular senescence.Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) in Mycobacterium tuberculosis leads to reduced virulence in a mouse model of infection.Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming.c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity.An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway.STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

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P2860

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.

http://www.wikidata.org/entity/Q34151349

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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Infection and Immunity

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The N-ethyl-N-nitrosourea-indu ...... enes and cyclic dinucleotides.

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Chris S Rae

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Daniel A Portnoy

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Jakob von Moltke

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Joshua J Woodward

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Kathryn M Monroe

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Katia Sotelo-Troha

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Russell E Vance

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Sky W Brubaker

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Yoshihiro Hayakawa

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P2860

IFI16 is an innate immune sensor for intracellular DNA

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

Roles of cyclic diguanylate in the regulation of bacterial pathogenesis

A census of membrane-bound and intracellular signal transduction proteins in bacteria: bacterial IQ, extroverts and introverts

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

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688-694

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10.1128/IAI.00999-10

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2

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79

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John-Demian Sauer

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2010-11-22T00:00:00Z

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21098106

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Listeria monocytogenes

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3028833

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