Multiple factors contribute to inefficient prenylation of Rab27a in Rab prenylation diseases.
about
Cargos and genes: insights into vesicular transport from inherited human diseaseRecent advances and future prospects in choroideremiaA Comprehensive Analysis of Choroideremia: From Genetic Characterization to Clinical PracticeThe role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cellsDistinct actions of Rab3 and Rab27 GTPases on late stages of exocytosis of insulin.A novel statin-mediated "prenylation block-and-release" assay provides insight into the membrane targeting mechanisms of small GTPases.The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.Multiple domain insertions and losses in the evolution of the Rab prenylation complex.Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patientsSilencing of the CHM gene alters phagocytic and secretory pathways in the retinal pigment epitheliumNovel 47.5-kb deletion in RAB27A results in severe Griscelli Syndrome Type 2.Rab GTPase prenylation hierarchy and its potential role in choroideremia diseaseImpaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function.Gene therapy for choroideremia using an adeno-associated viral (AAV) vector.Pathogenic mechanisms and the prospect of gene therapy for choroideremia.Retinal Gene Therapy: Current Progress and Future Prospects.Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.The Spectrum of CHM Gene Mutations in Choroideremia and Their Relationship to Clinical Phenotype.Recent advances in chemical proteomics: exploring the post-translational proteome.Rab protein evolution and the history of the eukaryotic endomembrane system.Prenylation defects in inherited retinal diseases.Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation.Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity.Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosisAdeno-associated virus 8-mediated gene therapy for choroideremia: preclinical studies in in vitro and in vivo models.Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity.Statins reduce amyloid-beta production through inhibition of protein isoprenylation.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A.
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P2860
Multiple factors contribute to inefficient prenylation of Rab27a in Rab prenylation diseases.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Multiple factors contribute to ...... a in Rab prenylation diseases.
@ast
Multiple factors contribute to ...... a in Rab prenylation diseases.
@en
Multiple factors contribute to ...... a in Rab prenylation diseases.
@nl
type
label
Multiple factors contribute to ...... a in Rab prenylation diseases.
@ast
Multiple factors contribute to ...... a in Rab prenylation diseases.
@en
Multiple factors contribute to ...... a in Rab prenylation diseases.
@nl
prefLabel
Multiple factors contribute to ...... a in Rab prenylation diseases.
@ast
Multiple factors contribute to ...... a in Rab prenylation diseases.
@en
Multiple factors contribute to ...... a in Rab prenylation diseases.
@nl
P2860
P50
P356
P1476
Multiple factors contribute to ...... a in Rab prenylation diseases.
@en
P2860
P304
46798-46804
P356
10.1074/JBC.M307799200
P407
P577
2003-08-25T00:00:00Z