Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders - Wikidata - wikimedia - TriplyDB

Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

http://www.wikidata.org/entity/Q34358701

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Glutamatergic targets for new alcohol medications Consolidation and translation regulation mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels.Contribution of P2X4 receptors to ethanol intake in male C57BL/6 mice.Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse.Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain.Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors.Distinct miRNA expression in dorsal striatal subregions is associated with risk for addiction in rats.An emerging role for the Mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction.Long-lasting alterations in membrane properties, k(+) currents, and glutamatergic synaptic currents of nucleus accumbens medium spiny neurons in a rat model of alcohol dependence.Ivermectin reduces alcohol intake and preference in mice.Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus).Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.S6 Kinase Reflects and Regulates Ethanol-Induced Sedation.Glutamatergic plasticity and alcohol dependence-induced alterations in reward, affect and cognition.Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization.Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine.The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors Retrograde changes in presynaptic function driven by dendritic mTORC1.The First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens Dopamine D1 Receptor Neurons.Enhanced AMPA receptor activity increases operant alcohol self-administration and cue-induced reinstatement New insights on neurobiological mechanisms underlying alcohol addiction.Effects of alcohol on the membrane excitability and synaptic transmission of medium spiny neurons in the nucleus accumbens.mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats Functional regulation of PI3K-associated signaling in the accumbens by binge alcohol drinking in male but not female mice.Predictable chronic mild stress in adolescence increases resilience in adulthood.Sex and the Lab: An Alcohol-Focused Commentary on the NIH Initiative to Balance Sex in Cell and Animal Studies.Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse.Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors.mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors.Signaling pathways mediating alcohol effects.Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brain Dendritic protein synthesis in the normal and diseased brain.mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse.Synaptic adaptations by alcohol and drugs of abuse: changes in microRNA expression and mRNA regulation.Molecular mechanisms underlying alcohol-drinking behaviours Alcohol-dependent molecular adaptations of the NMDA receptor system.Chromatin remodeling--a novel strategy to control excessive alcohol drinking.Responses to ethanol in C57BL/6 versus C57BL/6 × 129 hybrid mice.

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Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

http://www.wikidata.org/entity/Q34358701

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Role for mammalian target of r ...... ying alcohol-related disorders

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Role for mammalian target of r ...... ying alcohol-related disorders

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Role for mammalian target of r ...... ying alcohol-related disorders

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Role for mammalian target of r ...... ying alcohol-related disorders

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Role for mammalian target of r ...... ying alcohol-related disorders

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Role for mammalian target of r ...... ying alcohol-related disorders

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Proceedings of the National Academy of Sciences of the United States of America

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Role for mammalian target of r ...... ying alcohol-related disorders

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Dorit Ron

http://www.w3.org/2001/XMLSchema#string

Jérémie Neasta

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Quinn Yowell

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Sami Ben Hamida

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Sebastien Carnicella

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P2860

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior

NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.

Neurocircuitry of addiction

mTOR signaling: at the crossroads of plasticity, memory and disease

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

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20093-20098

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107

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2993345

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