Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
about
The nuclear envelopathies and human diseasesEmerin-prelamin A interplay in human fibroblastsTargeting protein prenylation in progeriaPhenotype and course of Hutchinson-Gilford progeria syndromeBlocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndromeModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesMouse models of laminopathiesSorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelopeCardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- miceLaminopathies and the long strange trip from basic cell biology to therapyPrelamin A farnesylation and progeroid syndromesProgeria of stem cells: stem cell exhaustion in Hutchinson-Gilford progeria syndromeNuclear lamins are differentially expressed in retinal neurons of the adult rat retinaZMPSTE24 defends against influenza and other pathogenic virusesProtein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defectIntermediate filaments: a historical perspectiveDisheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies.Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1.Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.The posttranslational processing of prelamin A and disease.DNA damage and laminsImpact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.Nuclear lamins and neurobiology.Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.Good news in the nuclear envelope: loss of lamin A might be a gain.Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin.Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatinDirected targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins.Investigating the purpose of prelamin A processingGeneration of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/CStabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrestMice that express farnesylated versions of prelamin A in neurons develop achalasia.Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases.Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.Mouse models of the laminopathies.HIV protease inhibitors and nuclear lamin processing: getting the right bells and whistles.Understanding the roles of nuclear A- and B-type lamins in brain development.Type-I prenyl protease function is required in the male germline of Drosophila melanogaster.
P2860
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P2860
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@ast
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@en
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@nl
type
label
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@ast
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@en
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@nl
prefLabel
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@ast
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@en
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@nl
P2093
P2860
P356
P1476
Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
@en
P2093
Bryant Gavino
C Frank Bennett
Colin L Stewart
Jan Lammerding
Jennifer K Ng
Loren G Fong
Margarita Meta
Martin O Bergo
Nathan Coté
Richard T Lee
P2860
P304
P356
10.1172/JCI27125
P407
P577
2006-03-01T00:00:00Z