CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
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The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motilityAnoikis resistance: an essential prerequisite for tumor metastasisFor robust big data analyses: a collection of 150 important pro-metastatic genesKAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancerCDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production.Characterization of functional reprogramming during osteoclast development using quantitative proteomics and mRNA profiling.Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers.Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformationBlocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.Increased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants.Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migrationThe Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domainADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis.CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinasesIdentification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patientsDysregulated expression of cell surface glycoprotein CDCP1 in prostate cancerCell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment.Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanismsCDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis.Cell surface remodeling by plasmin: a new function for an old enzyme.Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer.New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.Loss of CDCP1 expression promotes invasiveness and poor prognosis in esophageal squamous cell carcinoma.EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells.In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signalingInfrared spectral signatures of CDCP1-induced effects in colon carcinoma cells.The tyrosine phosphatase SHP2 associates with CUB domain-containing protein-1 (CDCP1), regulating its expression at the cell surface in a phosphorylation-dependent mannerHIF-2α regulates CDCP1 to promote PKCδ-mediated migration in hepatocellular carcinoma.miR-198 functions as a tumor suppressor in breast cancer by targeting CUB domain-containing protein 1.Involvement of Src in the Adaptation of Cancer Cells under Microenvironmental Stresses.Identification of key genes fluctuated induced by avian leukemia virus (ALV-J) infection in chicken cells.Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple Negative Breast Cancer.Prognostic Significance of CDCP1 Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion and Migration.YAP/TAZ Activation as a Target for Treating Metastatic Cancer.CIZ/NMP4 is expressed in B16 melanoma and forms a positive feedback loop with RANKL to promote migration of the melanoma cells
P2860
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P2860
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@ast
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@en
CUB-domain-containing protein 1
@nl
type
label
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@ast
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@en
CUB-domain-containing protein 1
@nl
prefLabel
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@ast
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@en
CUB-domain-containing protein 1
@nl
P2093
P2860
P356
P1476
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
@en
P2093
Forest M White
Jeffrey Schindler
Kwabena Badu-Nkansah
Shao-En Ong
P2860
P304
P356
10.1073/PNAS.1017228108
P407
P577
2011-01-10T00:00:00Z