CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis. - Wikidata - wikimedia - TriplyDB

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

http://www.wikidata.org/entity/Q34534040

about

The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility Anoikis resistance: an essential prerequisite for tumor metastasis For robust big data analyses: a collection of 150 important pro-metastatic genes KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production.Characterization of functional reprogramming during osteoclast development using quantitative proteomics and mRNA profiling.Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers.Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.Increased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants.Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734 The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis.CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment.Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis.Cell surface remodeling by plasmin: a new function for an old enzyme.Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer.New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.Loss of CDCP1 expression promotes invasiveness and poor prognosis in esophageal squamous cell carcinoma.EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells.In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling Infrared spectral signatures of CDCP1-induced effects in colon carcinoma cells.The tyrosine phosphatase SHP2 associates with CUB domain-containing protein-1 (CDCP1), regulating its expression at the cell surface in a phosphorylation-dependent manner HIF-2α regulates CDCP1 to promote PKCδ-mediated migration in hepatocellular carcinoma.miR-198 functions as a tumor suppressor in breast cancer by targeting CUB domain-containing protein 1.Involvement of Src in the Adaptation of Cancer Cells under Microenvironmental Stresses.Identification of key genes fluctuated induced by avian leukemia virus (ALV-J) infection in chicken cells.Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple Negative Breast Cancer.Prognostic Significance of CDCP1 Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion and Migration.YAP/TAZ Activation as a Target for Treating Metastatic Cancer.CIZ/NMP4 is expressed in B16 melanoma and forms a positive feedback loop with RANKL to promote migration of the melanoma cells

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P2860

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

http://www.wikidata.org/entity/Q34534040

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

@ast

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

@en

CUB-domain-containing protein 1

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type

label

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

@ast

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

@en

CUB-domain-containing protein 1

@nl

prefLabel

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

@ast

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

@en

CUB-domain-containing protein 1

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

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P2093

Forest M White

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Hui Liu

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Jeffrey Schindler

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Kwabena Badu-Nkansah

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Shao-En Ong

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P2860

Involvement of chemokine receptors in breast cancer metastasis

GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis

Src family kinases in tumor progression and metastasis

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

Adhesion signaling by a novel mitotic substrate of src kinases

Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein

CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma

Integrins: versatility, modulation, and signaling in cell adhesion

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

Genomic analysis of metastasis reveals an essential role for RhoC

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