Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.
about
Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activityMicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb proteinSmall C-terminal domain phosphatase enhances snail activity through dephosphorylationAxin and GSK3- control Smad3 protein stability and modulate TGF- signalingReversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal TransitionsTGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapyTGF-β and BMP signaling in osteoblast differentiation and bone formationStructural genomics of protein phosphatasesTGFβ signalling in contextTGFbeta in CancerC-terminal domain (CTD) small phosphatase-like 2 modulates the canonical bone morphogenetic protein (BMP) signaling and mesenchymal differentiation via Smad dephosphorylationOff-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2Specific control of BMP signaling and mesenchymal differentiation by cytoplasmic phosphatase PPM1H.CTD small phosphatase like 2 (CTDSPL2) can increase ε- and γ-globin gene expression in K562 cells and CD34+ cells derived from umbilical cord blood.The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach; particularly increasing in mucosae of Helicobacter-associated gastritis.An emerging role for the miR-26 family in cardiovascular disease.Transforming growth factor-β and the hallmarks of cancer.Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-β-mediated growth inhibition.Viewing serine/threonine protein phosphatases through the eyes of drug designersAcute phosphate restriction leads to impaired fracture healing and resistance to BMP-2.Phosphorylation of Smad2/3 at the specific linker threonine residue indicates slow-cycling esophageal stem-like cells before re-entry to the cell cycle.Phosphorylation of Smad2/3 at specific linker threonine indicates slow-cycling intestinal stem-like cells before reentry to cell cycle.Retinoic acid promotes myogenesis in myoblasts by antagonizing transforming growth factor-beta signaling via C/EBPβSmad phosphoisoform signaling specificity: the right place at the right timeSmad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells.Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of Receptor-regulated Smads (R-Smads) to Ensure Transforming Growth Factor β (TGFβ)-mediated Germ Layer Induction in Xenopus Embryos.Transforming growth factor-β and smooth muscle differentiationThe Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein DegradationKaempferol Suppresses Transforming Growth Factor-β1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179.Phospho-specific Smad3 signaling: impact on breast oncogenesis.FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegansBone morphogenetic protein signaling in stem cells--one signal, many consequences.Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest.Retinoids regulate TGFbeta signaling at the level of Smad2 phosphorylation and nuclear accumulation.To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modificationsOTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.Drosophila Dullard functions as a Mad phosphatase to terminate BMP signaling.Phospho-control of TGF-beta superfamily signaling.
P2860
Q24323077-4FEB6A98-956F-4A83-B941-967B309AE3F8Q24601263-9FD20BCB-2B46-4B60-AB76-1F80549D020AQ24656011-9F4665CA-B227-40B6-A22C-40FFF3970C9BQ24685123-3A8450B6-49B4-470A-B604-CE7BD1C40B3FQ26771696-DCD9440E-3C1F-4D5C-B486-2C9061709044Q26862838-784A343E-F072-4B4F-AF13-C2A8C635C55AQ26995720-B90CC280-4162-4B59-9855-F82568EBC9E4Q27649211-27B89B77-9C90-4780-B5F4-078BA398062CQ28275410-F496C79B-5B13-4D28-BDC5-BE90BF930252Q28288866-B98924AD-3D61-4408-9910-A19D9E11D7BEQ28511256-6F45162D-7151-4075-B3B3-919877C68454Q28914776-1CEB612B-9144-4215-89C1-DF5147218795Q33701824-E6A79CF5-7A37-4B1A-BC26-B11509110BDFQ33713346-1D58BC2D-24AC-401F-8632-E20D1BE571DCQ33791954-FF1A768D-BE79-4702-9A8E-0A40968B9E57Q34115775-C741B7BE-C3CA-4A5C-AF5D-BC6E9102AC28Q34789300-E74158B6-2B3E-44EA-B0BA-2EC7FE617B5FQ35013177-B107A2C9-4384-443D-A6D5-B6946B98D50BQ35025142-1B2E0AEB-D0AD-44EC-B2A0-3F22DEF3D92CQ35146774-270843E4-AD6E-49EF-AE1F-6BCC4819040AQ35156052-362F43AB-AF8C-46A9-9E6F-DD3DCCFA8459Q35234341-049B7DFE-28B3-48BD-9ECC-27684B3CA78AQ35237708-D6EB0559-48C7-4E5A-A8AB-F49C24BECD46Q35426456-E3203E6C-C1B6-4AAA-B328-C4351A681B23Q35478946-88B3D92E-BB1C-4A24-B8E4-135F1F2FBE12Q35649316-76F945F3-D58C-47A4-ADE4-F3F6DF896623Q35837137-1158E4A7-151D-4258-8F5C-F9EFF387F4E3Q35852389-DCE1CF16-E6B3-481C-8643-10A8B02FC8C5Q35956614-DE7CE8DF-3710-4B73-AA4B-995D4954C615Q35990325-8EF1ABB6-32E7-4603-A0B6-4FC2EF932F86Q36116217-B0E7FA9D-D030-4F51-A58F-EAFF572DD25AQ36184673-3BBE705D-E7C6-47C3-A053-6355C7C43DCFQ36678015-AB432BBE-5DC3-4C3C-BFAD-46FDC3CD03ACQ36830221-486ED154-27BC-4597-9CA6-EAB86C8C09E6Q36870956-7C168AB8-0170-4816-92A3-4E974166856EQ37001195-7B043BF5-E1CD-40B5-ABB6-8F9C2F9EC742Q37128066-E90A8874-1825-4640-B0A7-C2572F3715A2Q37217722-76110615-7AC4-4A5C-9E0B-1600F82BAB47Q37220058-186CD788-9F73-43DF-B873-AA1DD19C36ACQ37359953-3166D0A4-8586-4C28-BB38-9FC33F823671
P2860
Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@ast
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@en
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@nl
type
label
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@ast
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@en
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@nl
prefLabel
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@ast
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@en
Dephosphorylation of the linke ...... g growth factor-beta pathways.
@nl
P2093
P2860
P356
P1476
Dephosphorylation of the linke ...... ng growth factor-beta pathways
@en
P2093
Ali H Brivanlou
Claudio Alarcón
Ermelinda Montalvo
Gopal Sapkota
Marie Knockaert
P2860
P304
40412-40419
P356
10.1074/JBC.M610172200
P407
P577
2006-11-02T00:00:00Z