Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
about
Centriole assembly and the role of Mps1: defensible or dispensable?Holding their own: the noncanonical roles of Smad proteinsStructural and mechanistic insights into Mps1 kinase activationPin1 promotes transforming growth factor-beta-induced migration and invasion.The MPS1 family of protein kinases.An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancerCellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment.Differential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signalingMip1 associates with both the Mps1 kinase and actin, and is required for cell cortex stability and anaphase spindle positioning.A motif from Lys216 to Lys222 in human BUB3 protein is a nuclear localization signal and critical for BUB3 function in mitotic checkpoint.Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint.Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration.TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells.Activin receptor inhibition by Smad2 regulates Drosophila wing disc patterning through BMP-response elements.Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition.Lysine acetyltransferase GCN5 potentiates the growth of non-small cell lung cancer via promotion of E2F1, cyclin D1, and cyclin E1 expressionA double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instabilityRegulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylationEffects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs.TTK/hMps1 mediates the p53-dependent postmitotic checkpoint by phosphorylating p53 at Thr18.Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation AssayPhospho-control of TGF-beta superfamily signaling.The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.Modulation of miR-21 signaling by MPS1 in human glioblastomaLinking cell structure to gene regulation: signaling events and expression controls on the model genes PAI-1 and CTGF.The crosstalk of RAS with the TGF-β family during carcinoma progression and its implications for targeted cancer therapy.Role of Smads in TGFβ signaling.Post-translational regulation of TGF-β receptor and Smad signaling.Axotomy-induced Smad1 activation promotes axonal growth in adult sensory neurons.Role of Radiation-induced TGF-beta Signaling in Cancer Therapy.Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption.The mitotic checkpoint protein kinase BUB1 is an engine in the TGF-β signaling apparatus.High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint.TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer
P2860
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P2860
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@ast
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@en
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@nl
type
label
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@ast
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@en
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@nl
prefLabel
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@ast
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@en
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
@nl
P2093
P2860
P356
P1476
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling
@en
P2093
David C Clarke
Songcheng Zhu
P2860
P304
18327-18338
P356
10.1074/JBC.M700636200
P407
P50
P577
2007-04-23T00:00:00Z