Functionally distinct insulin receptors generated by tissue-specific alternative splicing.
about
hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor genePPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancerAlternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissuesObesity and cancer, a case for insulin signalingThe Insulin/IGF System in Colorectal Cancer Development and Resistance to TherapyUnderstanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentInsulin receptor signaling in normal and insulin-resistant statesThe metabolic and mitogenic properties of basal insulin analoguesThe insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potentialIGF-IR Targeted Therapy: Past, Present and FutureThe IGF system in thyroid cancer: new concepts.Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2Engineering of insulin receptor isoform-selective insulin analoguesNonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdissInsulin stimulates the biosynthesis of chiro-inositol-containing phospholipids in a rat fibroblast line expressing the human insulin receptor.Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processingA comparative structural bioinformatics analysis of the insulin receptor family ectodomain based on phylogenetic information.Insulin analogs and cancer: a note of caution.Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.Role of insulin receptor substrates in the progression of hepatocellular carcinoma.Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer.The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes.Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey.The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.Membrane-associated and soluble granulocyte/macrophage-colony-stimulating factor receptor alpha subunits are independently regulated in HL-60 cellsSpecific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin.Regulation of human insulin receptor RNA splicing in vivo.Aberrant liver insulin receptor isoform a expression normalises with remission of type 2 diabetes after gastric bypass surgery.FOXO1 is regulated by insulin and IGF1 in pituitary gonadotropes.The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link.Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality.Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform AExon skipping by mutation of an authentic splice site of c-kit gene in W/W mouseInsulin analogs and cancer.The insulin receptor: a new target for cancer therapy.Insulin receptor isotype expression correlates with risk of non-insulin-dependent diabetes.Isoform-specific insulin receptor signaling involves different plasma membrane domains.Intrinsic Resistance to Cixutumumab Is Conferred by Distinct Isoforms of the Insulin ReceptorIGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718.Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy.
P2860
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P2860
Functionally distinct insulin receptors generated by tissue-specific alternative splicing.
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Functionally distinct insulin ...... specific alternative splicing.
@ast
Functionally distinct insulin ...... specific alternative splicing.
@en
Functionally distinct insulin ...... specific alternative splicing.
@nl
type
label
Functionally distinct insulin ...... specific alternative splicing.
@ast
Functionally distinct insulin ...... specific alternative splicing.
@en
Functionally distinct insulin ...... specific alternative splicing.
@nl
prefLabel
Functionally distinct insulin ...... specific alternative splicing.
@ast
Functionally distinct insulin ...... specific alternative splicing.
@en
Functionally distinct insulin ...... specific alternative splicing.
@nl
P2093
P2860
P1433
P1476
Functionally distinct insulin ...... specific alternative splicing.
@en
P2093
P2860
P304
P407
P577
1990-08-01T00:00:00Z