Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
about
Coordination of DNA damage responses via the Smc5/Smc6 complexInteraction between human MCM7 and Rad17 proteins is required for replication checkpoint signalingFunctional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylationDisruption of mechanisms that prevent rereplication triggers a DNA damage responseLoading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitroLoss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damageReplication protein A-mediated recruitment and activation of Rad17 complexesRegulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatinMms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase IIFission yeast Rad26 responds to DNA damage independently of Rad3Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNABub3-BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomesHuman RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaksAn N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair.Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repairYeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA.Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damageTopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpointQuaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activitiesATR: an essential regulator of genome integritySgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsThe yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damageUdu deficiency activates DNA damage checkpoint.BubR1- and Polo-coated DNA tethers facilitate poleward segregation of acentric chromatids.The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence.A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break.Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint.Viral transport of DNA damage that mimics a stalled replication fork.Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage.Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences.Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilizationThe checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint.Function of a conserved checkpoint recruitment domain in ATRIP proteins.Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres.
P2860
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P2860
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@ast
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@en
type
label
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@ast
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@en
prefLabel
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@ast
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@en
P2093
P2860
P356
P1433
P1476
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
@en
P2093
P2860
P304
P356
10.1101/GAD.903501
P577
2001-11-01T00:00:00Z