Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells.
about
Glutamine stimulates biosynthesis and secretion of insulin-like growth factor 2 (IGF2), an autocrine regulator of beta cell mass and function.NFAT targets signaling molecules to gene promoters in pancreatic β-cells.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationChREBP mediates glucose-stimulated pancreatic β-cell proliferation.The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.Post-Transplant Diabetes Mellitus: Causes, Treatment, and Impact on OutcomesAblation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterasesTrimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in miceDirect autocrine action of insulin on β-cells: does it make physiological sense?Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemiaJunctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion.Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin ReceptorTargeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2.Diabetes mellitus--advances and challenges in human β-cell proliferation.Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation.Novel factors modulating human β-cell proliferation.Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets.Glucose- or insulin resistance-mediated β-cell replication: PKCζ integrates the proliferative signalingGrowth receptor binding protein 10 inhibits glucose-stimulated insulin release from pancreatic β-cells associated with suppression of the insulin/insulin-like growth factor-1 signalling pathway.Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells.(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives.Na+/Ca2+ Exchanger a Druggable Target to Promote β-Cell Proliferation and Function.Cellular signaling pathways regulating β-cell proliferation as a promising therapeutic target in the treatment of diabetes
P2860
Q34509707-F0FF2915-913D-470A-9F7C-28B51876A361Q35055005-F84403EF-137C-4735-A3ED-C4835D2FB6DBQ35942505-80FD2FEF-2F79-4078-B8B0-5C99F16B84FFQ36109313-FBDB8A6B-7A17-454A-BABF-EEEBDECE4493Q36217634-16E850B3-D553-4CCD-96A2-EE6484F3EFC3Q36402679-D0627DE0-96FF-4B5F-B35C-EE8C2C604F15Q36541052-92A83B0E-6B81-456A-B073-268D714C2960Q36579585-54038681-55AE-4550-B71E-1A84B0E28691Q36862098-A924F825-B6C2-4440-957A-99369E5D0BDBQ37014947-12E12578-F181-4769-A63C-EBEE012A2DE8Q37251144-AACF4126-D792-43DF-ABB2-C9DC3F876BFAQ37482839-DB463AF0-ECDB-44CC-9538-325147360A2EQ37597058-2A1F73AA-7523-45C3-B99F-71F054A0BF09Q37649339-F3BC0D92-60BA-4151-A325-03AF874157A4Q38224544-9B696C8E-6F7E-4488-8354-A5A22ECC40C9Q38358004-530184D0-6C5A-4154-B7EB-DE26449DBECDQ38912442-00805399-C9C1-46D6-96B7-561F137CE4BDQ38951158-D5F8ADBC-5005-48EC-BE30-1BB2AC06D0CFQ42152165-431BE935-FAF0-405C-A56C-C314CE78A1B5Q42174326-DE8453EF-5F56-4BFE-AB91-DEDB1A66E9F1Q42318776-4A213961-BDCE-4B90-BA87-3EA10363A326Q44039759-47F8D904-D986-46FA-B253-309161CFAEFBQ51040538-5E555D62-07E6-4E9F-A04E-55B4FB06E2B6Q52714852-41EB95F5-3B91-49B9-A186-27E6F660EE65Q55315068-C16282CC-AD9D-4CCE-B2A1-F43BDC9B8F32Q58784217-E4C76B3A-E4FD-49A1-813A-540186C121A1
P2860
Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@ast
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@en
type
label
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@ast
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@en
prefLabel
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@ast
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@en
P2093
P2860
P356
P1433
P1476
Specific glucose-induced contr ...... mary pancreatic islet β-cells.
@en
P2093
Christopher J Rhodes
Damien Demozay
Isabelle Briaud
Ramila Shah
Shin Tsunekawa
P2860
P304
P356
10.2337/DB11-0341
P407
P577
2011-09-22T00:00:00Z