A cell cycle-regulated inhibitor of cyclin-dependent kinases.
about
Classification of intrinsically disordered regions and proteinsp27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle controlInteraction and colocalization of PGP9.5 with JAB1 and p27(Kip1)CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephalyCyclin-binding motifs are essential for the function of p21CIP1Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrestCRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisTransforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsTransforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancerDeregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerCaspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasionCrystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 proteinDown-regulation of telomerase activity in malignant lymphomas by radiation and chemotherapeutic agentsRedistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiationCyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cellsCommon and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse modelEffects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplicationStructural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversityProliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell linesPrognostic implications of expression of the cell cycle inhibitor protein p27Kip1.The cyclin-dependent kinase inhibitor p27(Kip1) induces N-terminal proteolytic cleavage of cyclin A.Regulation of exit from quiescence by p27 and cyclin D1-CDK4.Circadian variation in expression of G1 phase cyclins D1 and E and cyclin-dependent kinase inhibitors p16 and p21 in human bowel mucosaPhosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27Cell cycle and transcriptional control of human myeloid leukemic cells by transforming growth factor beta.Role of p42/p44 mitogen-activated-protein kinase and p21waf1/cip1 in the regulation of vascular smooth muscle cell proliferation by nitric oxide.Confluence of vascular endothelial cells induces cell cycle exit by inhibiting p42/p44 mitogen-activated protein kinase activity.Novel markers of left ventricular hypertrophy in uremia.The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.A novel role of proteasomal β1 subunit in tumorigenesis.p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27 Kip1.Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical regionp27Kip1 inhibition of GRB2-SOS formation can regulate Ras activation.Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia.Reduced levels of the cell-cycle inhibitor p27Kip1 in epithelial dysplasia and carcinoma of the oral cavity.Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways.Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-MycCytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation.
P2860
Q22061736-B447B074-CC41-4122-BF90-F9F04A57CEA5Q24294568-5AEE97D0-A9AB-435D-9AC4-0DD0B5537499Q24297854-929CB725-C4C6-4D0F-A88C-ACF4DEA9031AQ24300283-8CDBC79A-F915-4FE8-92AE-B61114E145CEQ24315121-8C9025E2-B5BA-4AD3-AD96-17D94715C2D3Q24316125-368E2332-16F4-4D29-AFD6-9FE214087A81Q24537257-24CE9DFC-8612-4DB0-AE84-87830B9CFFBDQ24540387-E9769504-88F7-4E8F-891E-B066E1E6FC45Q24646540-D5B75F6D-E502-4BD7-B78E-1A2CE2857728Q24793291-50212A9D-FD43-4F80-BF49-FC0F54B245BDQ24803723-EE817093-5C16-47C6-A220-A17ED84B952EQ27309926-A49CBD9C-7DA7-4DA4-9013-74D5480990F9Q27631578-F50DC97F-A549-4174-99DE-47CD789F5E28Q28345325-A64057C6-C921-48F3-801A-728A96EA1977Q28507371-C567E7FC-B6FE-418E-9697-A50B6FDFF768Q28585746-D386B3AD-711B-4159-806B-A7AA52F65D89Q28588011-B06AD954-988A-4716-B138-6633E612E01FQ28611456-668F67B2-A77B-4F89-A285-9EB27E58FBDFQ28910326-D4BEF551-1646-4F56-864E-6D47696400BFQ30492978-8888E211-83F2-43A6-A2A2-F42677A1B236Q33538422-66B11D66-33A8-4468-BD6D-F80458393A6CQ33584588-B6A784C7-28C0-447D-BBBD-A6F8CF739C92Q33781529-DD277740-5580-45BB-98E4-F8A9933F8438Q33867338-D7F67085-1B6C-47B1-9A60-4BEB9BCB06FEQ33887383-5C1006C2-C7AA-456A-93A7-A4DCC4359C0AQ33929808-4EDDDD1B-EAA0-4806-AB12-7DE8D2601C53Q33948118-8B2ED707-C1C7-4EA1-80A2-6E2726E6D48FQ33957717-E3743BCA-B1FA-4914-8ADA-5E141C062E43Q34074943-A8D03F54-B02B-4109-941C-F823F027BB26Q34158996-9806FE2B-86A3-4C91-A100-136FDE0694F5Q34347861-8AEB4808-4363-4318-B603-81E7CD0BEA83Q34659823-BC5B8887-0A2D-409A-8CA1-7F6896572464Q34733508-E5129964-A519-4E54-9654-F0F98978BB54Q34880437-3268D55A-DF47-4A12-9994-7661553FAE27Q35002490-026463C3-BAE8-42A9-8E0C-37E1BF09BE7DQ35009496-48876920-8ECE-4F48-99F9-78BE0822FEC4Q35763759-FA26307F-3B26-4900-BDB9-D33FFEE3288CQ35832449-617B89C2-F95E-4031-AD78-6FB86415A2D5Q35915994-94505ACF-DDEC-4F19-AE7A-29E96A5BBADEQ35958293-3E18D5C3-C107-4831-BF54-5419695245C1
P2860
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@ast
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@en
type
label
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@ast
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@en
prefLabel
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@ast
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@en
P2093
P2860
P356
P1476
A cell cycle-regulated inhibitor of cyclin-dependent kinases.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.12.5291
P407
P577
1994-06-01T00:00:00Z