Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells - Wikidata - wikimedia - TriplyDB

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

http://www.wikidata.org/entity/Q35673793

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Induction of central tolerance by the factor Aire: molecular and epigenetic regulation The Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central Tolerance Role of viruses and bacteria-virus interactions in autoimmunity Thymic epithelial cell development and differentiation: cellular and molecular regulation Promiscuous Gene Expression in the Thymus: A Matter of Epigenetics, miRNA, and More?Novel Findings into AIRE Genetics and Functioning: Clinical Implications Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE.Transcriptional regulation and its misregulation in disease.Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes.Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells Aire controls gene expression in the thymic epithelium with ordered stochasticity Central tolerance to self revealed by the autoimmune regulator.Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance.A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.Differential splicing across immune system lineages Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity.MYC and transcription elongation.Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells.An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.Thymic epithelial cell development and its dysfunction in human diseases.Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells.Medullary thymic epithelial cells, the indispensable player in central tolerance.Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases.MYC degradation The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy.AIRE: From promiscuous molecular partnerships to promiscuous gene expression.Thymic stromal cell subsets for T cell development.AIRE expands: new roles in immune tolerance and beyond.Autoimmune regulator and self-tolerance - molecular and clinical aspects.Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator)Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla.The transcriptional regulator Aire binds to and activates super-enhancers.

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P2860

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

http://www.wikidata.org/entity/Q35673793

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

@zh-cn

name

Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

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Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

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type

label

Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

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Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

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prefLabel

Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

@ast

Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

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PNAS.1119351109

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Proceedings of the National Academy of Sciences of the United States of America

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Aire unleashes stalled RNA pol ...... ion in thymic epithelial cells

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Christophe Benoist

http://www.w3.org/2001/XMLSchema#string

Diane Mathis

http://www.w3.org/2001/XMLSchema#string

Hideyuki Yoshida

http://www.w3.org/2001/XMLSchema#string

Jakub Abramson

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Peter B Rahl

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P2860

Aire's partners in the molecular control of immunological tolerance

Human mediator subunit MED26 functions as a docking site for transcription elongation factors

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

TIF1gamma controls erythroid cell fate by regulating transcription elongation

Domains in the SPT5 protein that modulate its transcriptional regulatory properties

c-Myc regulates transcriptional pause release

RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

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535-540

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2

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109

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Matthieu Giraud

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2011-12-27T00:00:00Z

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51954327

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22203960

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3258631

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